IJMDC. 2020; 4(6): 1016-1021

Updates on the use of anticoagulants for prevention of stroke: a systematic review

Authors: Sumayyah Almarshedy, Fahad Abdullah M. Alshammari.

ABSTRACT

Stroke is a common neurological disease, especially in patients with atrial fibrillation. The use of antiplatelets showed a significant benefit and reduction in mortality. However, the use of anticoagulants in stroke prevention has been controversial. This study to review the medical literature to investigate the updates in the use of anticoagulants for stroke prevention in the past decade. The literature was evaluated through PubMed, Embase, Medline, and Ovid database in the duration between 2010 and 2020. The searching terms included were a combination of anticoagulation, stroke, and prevention. Following this, the results were refined to include only original research articles evaluating the use of anticoagulants in stroke patients. Eligible trials mentioned the type of anticoagulant that was used. A total of 1862 articles were recovered. After the exclusion of articles on animals and including only analyses on humans, 58 studies appeared. A total of eight studies were considered eligible, covering a total of 41,458 patients who had atrial fibrillation and required measures for stroke prevention. Three studies were observational cohort, whereas four studies were retrospective and one pharmacoeconomic study. It was concluded that anticoagulants in patients with CHADS2-VASC scored greater than or equal to two could prevent stroke in atrial fibrillation patients. new oral anticoagulants were preferred in non-valvular atrial fibrillation patients.

Keywords:
Anticoagulant, stroke, prevention, updates.


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Updates on the use of anticoagulants for prevention of stroke: a systematic review


Authors
Sumayyah Almarshedy
Teaching Assistant, Division of adult neurology, Department of Internal Medicine, Collage of Medicine, University of Hail, Hail, Saudi Arabia
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Fahad Abdullah M Alshammari
Emergency Physician, Division of adult Emergency medicine, Department of Emergency medical services, Collage of Medicine, University of Hail, Hail, Saudi Arabia.
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Correspondence to:
. Sumayyah Almarshedy, Teaching Assistant, Division of Adult Neurology, Department of Internal Medicine, University of Hail, Kingdom of Saudi Arabia.; dr.sumayyahalmarshedy@gmail.com

Publication history
Received 16 Apr 2020
Accepted 04 Jun 2020
Published online 13 Jun 2020
Published in print 25 Jun 2020

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Pubmed Style

Almarshedy S, Alshammari FAM. Updates on the use of anticoagulants for prevention of stroke: a systematic review. IJMDC. 2020; 4(6): 1016-1021. doi:10.24911/IJMDC.51-1587052779


Web Style

Almarshedy S, Alshammari FAM. Updates on the use of anticoagulants for prevention of stroke: a systematic review. http://www.ijmdc.com/?mno=99834 [Access: July 14, 2020]. doi:10.24911/IJMDC.51-1587052779


AMA (American Medical Association) Style

Almarshedy S, Alshammari FAM. Updates on the use of anticoagulants for prevention of stroke: a systematic review. IJMDC. 2020; 4(6): 1016-1021. doi:10.24911/IJMDC.51-1587052779


Vancouver/ICMJE Style

Almarshedy S, Alshammari FAM. Updates on the use of anticoagulants for prevention of stroke: a systematic review. IJMDC. (2020), [cited July 14, 2020]; 4(6): 1016-1021. doi:10.24911/IJMDC.51-1587052779


Harvard Style

Almarshedy, S. & Alshammari, . F. A. M. (2020) Updates on the use of anticoagulants for prevention of stroke: a systematic review. IJMDC, 4 (6), 1016-1021. doi:10.24911/IJMDC.51-1587052779


Turabian Style

Almarshedy, Sumayyah, and Fahad Abdullah M. Alshammari. 2020. Updates on the use of anticoagulants for prevention of stroke: a systematic review. International Journal of Medicine in Developing Countries, 4 (6), 1016-1021. doi:10.24911/IJMDC.51-1587052779


Chicago Style

Almarshedy, Sumayyah, and Fahad Abdullah M. Alshammari. "Updates on the use of anticoagulants for prevention of stroke: a systematic review." International Journal of Medicine in Developing Countries 4 (2020), 1016-1021. doi:10.24911/IJMDC.51-1587052779


MLA (The Modern Language Association) Style

Almarshedy, Sumayyah, and Fahad Abdullah M. Alshammari. "Updates on the use of anticoagulants for prevention of stroke: a systematic review." International Journal of Medicine in Developing Countries 4.6 (2020), 1016-1021. Print. doi:10.24911/IJMDC.51-1587052779


APA (American Psychological Association) Style

Almarshedy, S. & Alshammari, . F. A. M. (2020) Updates on the use of anticoagulants for prevention of stroke: a systematic review. International Journal of Medicine in Developing Countries, 4 (6), 1016-1021. doi:10.24911/IJMDC.51-1587052779


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