Original Article

IJMDC. 2019; 3(1): 26-29

Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia

Authors: Dalya Alqarni, Asma Alshehri, Raghad Aldehasi, Lujain Al-Sayegh, Dania Binrahma, Naeem AlShoaibi.

ABSTRACT

Background: Metformin is a common drug used for antihyperglycemic therapy in type 2 diabetes. Additionally, intravenous (IV) contrast may be administered when using the various imaging techniques to enhance the visualization of body structures, and deterioration of renal function and lactic acidosis - contrast-induced nephropathy (CIN) - may occasionally happen. The purpose of this research was to assess the current guideline of withholding metformin therapy in patients undergoing contrast-enhanced procedures in both the emergency and inpatient settings. Methodology: A retrospective study was conducted for all patients who were on metformin and underwent a contrast-enhanced imaging procedure (requiring IV contrast) between January and June 2016 at King Abdulaziz University Hospital in Jeddah, Saudi Arabia. Results: This study involved 107 patients on metformin who received a contrast-enhanced imaging procedure. Out of 107 patients, 26 were admitted through the ER. Independent t-tests were performed to compare GFR and creatinine, before and after the procedure in both, ER and ward patients; they all had non-significant associations. Conclusion: In this study none of the ER patients stopped their metformin before they were administered IV contrast.

Keywords:
Metformin, Creatinine, GFR, Contrast, Emergency


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Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia


Authors
Dalya Alqarni
Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
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Asma Alshehri
Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Raghad Aldehasi
Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Lujain Al-Sayegh
Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Dania Binrahma
Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
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Naeem AlShoaibi
Department of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
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Correspondence to:
. Dalya Alqarni, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; alqarnidalya@gmail.com

Publication history
Published online 01 Jan 1970
Received 05 Dec 2018
Accepted 21 Dec 2018
Published in print 01 Feb 2019

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Pubmed Style

Alqarni D, Alshehri A, Aldehasi R, Al-Sayegh L, Binrahma D, AlShoaibi N. Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. IJMDC. 2019; 3(1): 26-29. doi:10.24911/IJMDC.51-1543999258


Web Style

Alqarni D, Alshehri A, Aldehasi R, Al-Sayegh L, Binrahma D, AlShoaibi N. Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. http://www.ijmdc.com/?mno=20293 [Access: April 22, 2019]. doi:10.24911/IJMDC.51-1543999258


AMA (American Medical Association) Style

Alqarni D, Alshehri A, Aldehasi R, Al-Sayegh L, Binrahma D, AlShoaibi N. Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. IJMDC. 2019; 3(1): 26-29. doi:10.24911/IJMDC.51-1543999258


Vancouver/ICMJE Style

Alqarni D, Alshehri A, Aldehasi R, Al-Sayegh L, Binrahma D, AlShoaibi N. Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. IJMDC. (2019), [cited April 22, 2019]; 3(1): 26-29. doi:10.24911/IJMDC.51-1543999258


Harvard Style

Alqarni, D., Alshehri, . A., Aldehasi, . R., Al-Sayegh, . L., Binrahma, . D. & AlShoaibi, . N. (2019) Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. IJMDC, 3 (1), 26-29. doi:10.24911/IJMDC.51-1543999258


Turabian Style

Alqarni, Dalya, Asma Alshehri, Raghad Aldehasi, Lujain Al-Sayegh, Dania Binrahma, and Naeem AlShoaibi. 2019. Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. International Journal of Medicine in Developing Countries, 3 (1), 26-29. doi:10.24911/IJMDC.51-1543999258


Chicago Style

Alqarni, Dalya, Asma Alshehri, Raghad Aldehasi, Lujain Al-Sayegh, Dania Binrahma, and Naeem AlShoaibi. "Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia." International Journal of Medicine in Developing Countries 3 (2019), 26-29. doi:10.24911/IJMDC.51-1543999258


MLA (The Modern Language Association) Style

Alqarni, Dalya, Asma Alshehri, Raghad Aldehasi, Lujain Al-Sayegh, Dania Binrahma, and Naeem AlShoaibi. "Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia." International Journal of Medicine in Developing Countries 3.1 (2019), 26-29. Print. doi:10.24911/IJMDC.51-1543999258


APA (American Psychological Association) Style

Alqarni, D., Alshehri, . A., Aldehasi, . R., Al-Sayegh, . L., Binrahma, . D. & AlShoaibi, . N. (2019) Metformin and intravenous contrast when time not help, A retrospective study at King Abdulaziz University Hospital, Jeddah, Saudi Arabia. International Journal of Medicine in Developing Countries, 3 (1), 26-29. doi:10.24911/IJMDC.51-1543999258


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