IJMDC. 2019; 3(9): 01-04

Quantitative analysis of diffusion-weighted imaging in high-risk and newly diagnosed breast cancer patients: a systematic review

Authors: Basmah Altuwayjiri.

ABSTRACT

Diffusion Weighted Imaging (DWI) is a Magnetic Resonance Imaging (MRI) sequence that can characterize the overall movement of water to assess indirectly the microstructure inside a tissue. The objective of our study is to determine, in a systematic review, the diagnostic performance of quantitative DWI in high risk and newly diagnosed patients with breast lesions. English trials published between 2008 and 2018 were assessed to evaluate the diagnostic power of quantitative DWI in patients with breast lesions were revised and summarized regarding the inclusion and exclusion criteria in addition to characteristics of the lesions and the histopathological findings at morphological and/or dynamic levels. Among 96 eligible studies, covering a total of 649 patients and 771 breast lesions, of which, 401 were malignant and 370 were benign. 12 study were included in this systematic review that was published between 2008 and 2018, mean Apparent Diffusion Coefficient (ADC) measures of malignancy were ranging between 0.88 and 1.42 10-3 mm2/s. The mean ADC measure of benign lesions lied between 1.00 and 1.87 10-3 mm2/s. Quantitative DWI has a better specificity to distinguish between benign and malignant breast lesions in comparison to that of contrast-enhanced MRI. Though, large multi-center randomized control trials are needed to evaluate its clinical impact because of varying diffusion gradient factor and diagnosis threshold.

Keywords:
Breast cancer; Diffusion-weighted imaging


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Quantitative analysis of diffusion-weighted imaging in high-risk and newly diagnosed breast cancer patients: a systematic review


Authors
Basmah Altuwayjiri
Department of Medical Imaging, King Fahad Medical City, Riyadh, Saudi Arabia
PubMed articlesGoogle scholar articles


Correspondence to:
. Department of Medical Imaging, King Fahad Medical City, Riyadh, Saudi Arabia; dr.bassima@gmail.com

Publication history
Received 06 Oct 2018
Accepted 07 Jun 2019
Published online 29 Jul 2019
Published in print 15 Aug 2019

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Pubmed Style

Basmah Altuwayjiri. Quantitative analysis of diffusion-weighted imaging in high-risk and newly diagnosed breast cancer patients: a systematic review. IJMDC. 2019; 3(9): 01-04. doi:10.24911/IJMDC.51-1538825110


Web Style

Basmah Altuwayjiri. Quantitative analysis of diffusion-weighted imaging in high-risk and newly diagnosed breast cancer patients: a systematic review. http://www.ijmdc.com/?mno=11554 [Access: September 23, 2019]. doi:10.24911/IJMDC.51-1538825110


AMA (American Medical Association) Style

Basmah Altuwayjiri. Quantitative analysis of diffusion-weighted imaging in high-risk and newly diagnosed breast cancer patients: a systematic review. IJMDC. 2019; 3(9): 01-04. doi:10.24911/IJMDC.51-1538825110


Vancouver/ICMJE Style

Basmah Altuwayjiri. Quantitative analysis of diffusion-weighted imaging in high-risk and newly diagnosed breast cancer patients: a systematic review. IJMDC. (2019), [cited September 23, 2019]; 3(9): 01-04. doi:10.24911/IJMDC.51-1538825110


Harvard Style

Basmah Altuwayjiri (2019) Quantitative analysis of diffusion-weighted imaging in high-risk and newly diagnosed breast cancer patients: a systematic review. IJMDC, 3 (9), 01-04. doi:10.24911/IJMDC.51-1538825110


Turabian Style

Basmah Altuwayjiri. 2019. Quantitative analysis of diffusion-weighted imaging in high-risk and newly diagnosed breast cancer patients: a systematic review. International Journal of Medicine in Developing Countries, 3 (9), 01-04. doi:10.24911/IJMDC.51-1538825110


Chicago Style

Basmah Altuwayjiri. "Quantitative analysis of diffusion-weighted imaging in high-risk and newly diagnosed breast cancer patients: a systematic review." International Journal of Medicine in Developing Countries 3 (2019), 01-04. doi:10.24911/IJMDC.51-1538825110


MLA (The Modern Language Association) Style

Basmah Altuwayjiri. "Quantitative analysis of diffusion-weighted imaging in high-risk and newly diagnosed breast cancer patients: a systematic review." International Journal of Medicine in Developing Countries 3.9 (2019), 01-04. Print. doi:10.24911/IJMDC.51-1538825110


APA (American Psychological Association) Style

Basmah Altuwayjiri (2019) Quantitative analysis of diffusion-weighted imaging in high-risk and newly diagnosed breast cancer patients: a systematic review. International Journal of Medicine in Developing Countries, 3 (9), 01-04. doi:10.24911/IJMDC.51-1538825110


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