The association between interstitial cystitis and dyspareunia: a systematic review

Abdullah Abdu Ali Assiri; Abrar A Assiri; Rahaf Mudawi Saeed Almulfi; Ahmed Saeed S. Alqahtani; Wajd A. Alhadi; Abdulmajeed Mohammed Alqahtani; Mohammed Abdulrahman Aljaber Asiri; Najla Mohammed H. Alshehri; Sarah Yahya S. Mones; Saud Abdullah Bin Fudhayl; Merai Saeed Nasser Nasser

doi:10.24911/IJMDC.51-1735594952

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Online Published: 20 Jan 2025

IJMDC. 2025; 9(2): 487-492

doi: 10.24911/IJMDC.51-1735594952

The association between interstitial cystitis and dyspareunia: a systematic review

Abdullah Abdu Ali Assiri, Abrar A Assiri, Rahaf Mudawi Saeed Almulfi, Ahmed Saeed S. Alqahtani, Wajd A. Alhadi, Abdulmajeed Mohammed Alqahtani, Mohammed Abdulrahman Aljaber Asiri, Najla Mohammed H. Alshehri, Sarah Yahya S. Mones, Saud Abdullah Bin Fudhayl, Merai Saeed Nasser Nasser.

Abstract
We aimed to look at the evidence that connects dyspareunia with interstitial cystitis (IC). After a comprehensive search of four databases, 690 pertinent publications were found. Three hundred twenty-four full-text articles were examined after duplicates were eliminated using Rayyan QCRI and relevance was assessed; seven research finally satisfied the requirements for inclusion. A total of 629 women with IC were involved in seven trials. With a total incidence of 394 (62.6%), the prevalence of dyspareunia among patients with IC varied from 31.9% to 90%. IC significantly contributes to chronic pelvic pain and dyspareunia, particularly in younger women. Although dyspareunia tends to decrease with age, menopausal women continue to experience more discomfort during sex than non-menopausal women. The association between IC and sexual pain problems is further supported by case-control studies, which consistently demonstrate a greater prevalence of dyspareunia in patients with IC relative to controls. Many patients with IC report sharp pelvic pain, burning after intercourse, and prolonged discomfort, affecting both sexual and overall pelvic health. The review strongly indicates a close link between IC and dyspareunia, emphasizing how crucial it is to take IC into account while diagnosing persistent pelvic discomfort. Recognizing and addressing IC’s impact on sexual health can enhance patient care and quality of life. However, further longitudinal studies are necessary to better understand how dyspareunia develops in patients with IC and to explore potential interventions to alleviate its effects.

Key words: Interstitial cystitis; Bladder pain syndrome; Dyspareunia; Sexual health; Systematic review.

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Pubmed Style

Assiri AAA, Assiri AA, Almulfi RMS, Alqahtani ASS, Alhadi WA, Alqahtani AM, Asiri MAA, Alshehri NMH, Mones SYS, Fudhayl SAB, Nasser MSN. The association between interstitial cystitis and dyspareunia: a systematic review. IJMDC. 2025; 9(2): 487-492. doi:10.24911/IJMDC.51-1735594952

Web Style

Assiri AAA, Assiri AA, Almulfi RMS, Alqahtani ASS, Alhadi WA, Alqahtani AM, Asiri MAA, Alshehri NMH, Mones SYS, Fudhayl SAB, Nasser MSN. The association between interstitial cystitis and dyspareunia: a systematic review. https://www.ijmdc.com/?mno=235390 [Access: March 17, 2025]. doi:10.24911/IJMDC.51-1735594952

AMA (American Medical Association) Style

Assiri AAA, Assiri AA, Almulfi RMS, Alqahtani ASS, Alhadi WA, Alqahtani AM, Asiri MAA, Alshehri NMH, Mones SYS, Fudhayl SAB, Nasser MSN. The association between interstitial cystitis and dyspareunia: a systematic review. IJMDC. 2025; 9(2): 487-492. doi:10.24911/IJMDC.51-1735594952

Vancouver/ICMJE Style

Assiri AAA, Assiri AA, Almulfi RMS, Alqahtani ASS, Alhadi WA, Alqahtani AM, Asiri MAA, Alshehri NMH, Mones SYS, Fudhayl SAB, Nasser MSN. The association between interstitial cystitis and dyspareunia: a systematic review. IJMDC. (2025), [cited March 17, 2025]; 9(2): 487-492. doi:10.24911/IJMDC.51-1735594952

Harvard Style

Assiri, A. A. A., Assiri, . A. A., Almulfi, . R. M. S., Alqahtani, . A. S. S., Alhadi, . W. A., Alqahtani, . A. M., Asiri, . M. A. A., Alshehri, . N. M. H., Mones, . S. Y. S., Fudhayl, . S. A. B. & Nasser, . M. S. N. (2025) The association between interstitial cystitis and dyspareunia: a systematic review. IJMDC, 9 (2), 487-492. doi:10.24911/IJMDC.51-1735594952

Turabian Style

Assiri, Abdullah Abdu Ali, Abrar A Assiri, Rahaf Mudawi Saeed Almulfi, Ahmed Saeed S. Alqahtani, Wajd A. Alhadi, Abdulmajeed Mohammed Alqahtani, Mohammed Abdulrahman Aljaber Asiri, Najla Mohammed H. Alshehri, Sarah Yahya S. Mones, Saud Abdullah Bin Fudhayl, and Merai Saeed Nasser Nasser. 2025. The association between interstitial cystitis and dyspareunia: a systematic review. International Journal of Medicine in Developing Countries, 9 (2), 487-492. doi:10.24911/IJMDC.51-1735594952

Chicago Style

Assiri, Abdullah Abdu Ali, Abrar A Assiri, Rahaf Mudawi Saeed Almulfi, Ahmed Saeed S. Alqahtani, Wajd A. Alhadi, Abdulmajeed Mohammed Alqahtani, Mohammed Abdulrahman Aljaber Asiri, Najla Mohammed H. Alshehri, Sarah Yahya S. Mones, Saud Abdullah Bin Fudhayl, and Merai Saeed Nasser Nasser. "The association between interstitial cystitis and dyspareunia: a systematic review." International Journal of Medicine in Developing Countries 9 (2025), 487-492. doi:10.24911/IJMDC.51-1735594952

MLA (The Modern Language Association) Style

Assiri, Abdullah Abdu Ali, Abrar A Assiri, Rahaf Mudawi Saeed Almulfi, Ahmed Saeed S. Alqahtani, Wajd A. Alhadi, Abdulmajeed Mohammed Alqahtani, Mohammed Abdulrahman Aljaber Asiri, Najla Mohammed H. Alshehri, Sarah Yahya S. Mones, Saud Abdullah Bin Fudhayl, and Merai Saeed Nasser Nasser. "The association between interstitial cystitis and dyspareunia: a systematic review." International Journal of Medicine in Developing Countries 9.2 (2025), 487-492. Print. doi:10.24911/IJMDC.51-1735594952

APA (American Psychological Association) Style

Assiri, A. A. A., Assiri, . A. A., Almulfi, . R. M. S., Alqahtani, . A. S. S., Alhadi, . W. A., Alqahtani, . A. M., Asiri, . M. A. A., Alshehri, . N. M. H., Mones, . S. Y. S., Fudhayl, . S. A. B. & Nasser, . M. S. N. (2025) The association between interstitial cystitis and dyspareunia: a systematic review. International Journal of Medicine in Developing Countries, 9 (2), 487-492. doi:10.24911/IJMDC.51-1735594952

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