Portal vein thrombosis with associated splenic infarction, gastroesophageal varices, and colorectal neoplasms featuring high-grade dysplasia

Sarrah Awad Alshammari; Salwah Mohammed Qaysi; Mohamed Shawky Elbayoumy

doi:10.24911/IJMDC.51-1734990103

2025, Vol: 9, Issue: 2

9 / 2Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

« Previous Article

Review Article
Online Published: 23 Jan 2025

IJMDC. 2025; 9(2): 463-469

doi: 10.24911/IJMDC.51-1734990103

Portal vein thrombosis with associated splenic infarction, gastroesophageal varices, and colorectal neoplasms featuring high-grade dysplasia

Sarrah Awad Alshammari, Salwah Mohammed Qaysi, Mohamed Shawky Elbayoumy.

Abstract
Portal vein thrombosis (PVT) is a rare but serious condition that can lead to significant complications such as portal hypertension and gastrointestinal ischemia. This report discusses a unique case of extensive PVT involving the mesenteric veins, splenic infarction, gastroesophageal varices, and colorectal neoplasms with high-grade dysplasia. A 55-year-old woman with no notable medical history presented with recurrent abdominal pain after meals, poor appetite, and occasional vomiting. Imaging studies showed thrombosis in the portal vein, splenic vein, superior mesenteric vein, and inferior mesenteric vein, along with signs of splenic infarction. Endoscopic examinations revealed grade I esophageal varices, type 2 gastroesophageal varices, and several polyps in the colon and rectum. Histopathological analysis confirmed the presence of tubulovillous adenomas with high-grade dysplasia in the rectum, raising concerns about potential malignancy. Laboratory tests indicated microcytic hypochromic anemia and an elevated International Normalized Ratio (INR), which required anticoagulation treatment with warfarin. This case illustrates the complexities involved in diagnosing and managing PVT and its complications, especially when colorectal neoplasia is also present. A multidisciplinary approach is essential to tackle the various challenges posed by this condition and to improve patient outcomes. Further research into the connections between thrombosis, malignancy, and hypercoagulability is crucial for enhancing understanding and treatment options.

Key words: Portal vein thrombosis; Splenic infarction Mesenteric vein thrombosiss; Gastroesophageal varices; Colorectal neoplasms; High-grade dysplasia; Endoscopic submucosal dissection.

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Sarrah Awad Alshammari Articles by Salwah Mohammed Qaysi Articles by Mohamed Shawky Elbayoumy
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

Alshammari SA, Qaysi SM, Elbayoumy MS. Portal vein thrombosis with associated splenic infarction, gastroesophageal varices, and colorectal neoplasms featuring high-grade dysplasia. IJMDC. 2025; 9(2): 463-469. doi:10.24911/IJMDC.51-1734990103

Web Style

Alshammari SA, Qaysi SM, Elbayoumy MS. Portal vein thrombosis with associated splenic infarction, gastroesophageal varices, and colorectal neoplasms featuring high-grade dysplasia. https://www.ijmdc.com/?mno=234392 [Access: March 17, 2025]. doi:10.24911/IJMDC.51-1734990103

AMA (American Medical Association) Style

Alshammari SA, Qaysi SM, Elbayoumy MS. Portal vein thrombosis with associated splenic infarction, gastroesophageal varices, and colorectal neoplasms featuring high-grade dysplasia. IJMDC. 2025; 9(2): 463-469. doi:10.24911/IJMDC.51-1734990103

Vancouver/ICMJE Style

Alshammari SA, Qaysi SM, Elbayoumy MS. Portal vein thrombosis with associated splenic infarction, gastroesophageal varices, and colorectal neoplasms featuring high-grade dysplasia. IJMDC. (2025), [cited March 17, 2025]; 9(2): 463-469. doi:10.24911/IJMDC.51-1734990103

Harvard Style

Alshammari, S. A., Qaysi, . S. M. & Elbayoumy, . M. S. (2025) Portal vein thrombosis with associated splenic infarction, gastroesophageal varices, and colorectal neoplasms featuring high-grade dysplasia. IJMDC, 9 (2), 463-469. doi:10.24911/IJMDC.51-1734990103

Turabian Style

Alshammari, Sarrah Awad, Salwah Mohammed Qaysi, and Mohamed Shawky Elbayoumy. 2025. Portal vein thrombosis with associated splenic infarction, gastroesophageal varices, and colorectal neoplasms featuring high-grade dysplasia. International Journal of Medicine in Developing Countries, 9 (2), 463-469. doi:10.24911/IJMDC.51-1734990103

Chicago Style

Alshammari, Sarrah Awad, Salwah Mohammed Qaysi, and Mohamed Shawky Elbayoumy. "Portal vein thrombosis with associated splenic infarction, gastroesophageal varices, and colorectal neoplasms featuring high-grade dysplasia." International Journal of Medicine in Developing Countries 9 (2025), 463-469. doi:10.24911/IJMDC.51-1734990103

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Alshammari, S. A., Qaysi, . S. M. & Elbayoumy, . M. S. (2025) Portal vein thrombosis with associated splenic infarction, gastroesophageal varices, and colorectal neoplasms featuring high-grade dysplasia. International Journal of Medicine in Developing Countries, 9 (2), 463-469. doi:10.24911/IJMDC.51-1734990103

Most Viewed Articles

Most Accessed Articles

Marginal adaptation of fixed prosthodontics
Shahad Mohammed Halawani, Sahar Amer Al-Harbi
IJMDC. 2017; 1(2): 78-84
» Abstract » doi: 10.24911/IJMDC.1.2.7

Parasites in central nervous system
Amal Ahmed Mohamed, Asmaa Mohamed Mansour
IJMDC. 2017; 1(2): 72-77
» Abstract » doi: 10.24911/IJMDC.1.2.6

Non-diabetic retinopathy: a case report
Hassan F. Alkwikbi, Nabil Mamon Abdelfattah, Haithem Mamon Abdelfattah
IJMDC. 2017; 1(1): 33-37
» Abstract » doi: 10.24911/IJMDC.1.1.6

Vitamin D deficiency among high school female students in Riyadh
Sahar Mohsen Aldhafeeri, Fatemah Ibraheem Alrawaji, Abrar Mubarak Algharbi, Alanoud Abdullah Alhessan, Ayat Sami Qabaja, Ghaleah Abdulaziz Alnassar, Ghaliah Ofayn Alsulami, Mashael Belal Alrubaian, Norah Abdulaziz Alhatim, Salehah Salih Alotaibi, Zahra Ali Alkhamees
IJMDC. 2017; 1(1): 18-23
» Abstract » doi: 10.24911/IJMDC.1.1.4

Prognosis of chronic complications of diabetes mellitus (DM) after multiple events of diabetic ketoacidosis (DKA)
Baraa Faiez Rajab, Anwar Essa Alamrim, Ali Essa Alamri
IJMDC. 2019; 3(5): 474-479
» Abstract » doi: 10.24911/IJMDC.51-1546551993

Most Downloaded

Top Downloaded Articles

Anti-IL-17 markedly inhibited the in vitro granuloma induced by Schistosoma mansoni soluble egg antigen.
Asmaa Ezz, Irene S. Gmail, Fatma Elzahraa H. Salem, Rabab Salama, Soad Nady
IJMDC. 2018; 2(January 2018): 38-46
» Abstract » doi: 10.24911/IJMDC.2.1.7

Antibiotic Resistance Crisis
Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
IJMDC. 2019; 3(6): 561-564
» Abstract » doi: 10.24911/IJMDC.51-1549060699

The knowledge of mothers about children malnutrition and associated factors
Anas Abdulrahman Aljohani, Mujahid Abdulrahman Aljohani
IJMDC. 2020; 4(1): 7-11
» Abstract » doi: 10.24911/IJMDC.51-1541620358

Knowledge and attitude of caregivers of cerebral palsy children in Riyadh city
Abdulaziz Alruwaished, Baleegh Ali, Lubna Abdullah Alhowaimil , Abaraa adullah Alhowaimil, Najd Abdullah Alhowaimil, Aminah Alessa
IJMDC. 2020; 4(1): 12-17
» Abstract » doi: 10.24911/IJMDC.51-1547833051

Most Cited Articles

Most Cited Articles

Antibiotic Resistance Crisis
Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
IJMDC. 2019; 3(6): 561-564
» Abstract » doi: 10.24911/IJMDC.51-1549060699
Cited : 34 times [Click to see citing articles]

Prevalence of depression, anxiety and stress among diabetes mellitus patients in Arar, Northern Saudi Arabia
AMohammed Elamin Mukrim, Nujud Muteb D. Alshammari, Wurud Muteb D. Alshammari, Maali Subhi T. Alshammari, Yousef Nasif R. Alshammari, Abdulaziz Sael M. Alshammari, Maisa Hamad F. Alanazi, Abdulelah Abdulrhman F. Alzammam, Muharib Mana M. Alshammari, Slwa Khaled Abu Asyah, Aseel Jamal Alzuhayri, Mushref Saeid Alshammari
IJMDC. 2019; 3(3): 229-233
» Abstract » doi: 10.24911/IJMDC.51-1542576396
Cited : 8 times [Click to see citing articles]

Knowledge, attitude, and practice of breast self-examination toward breast cancer among female students at King Saud University in Riyadh, Saudi Arabia
Abdullah Nasser Alomair, Dania Ghazi Felemban, Mohannad Sami Felemban, Jameel Abdullah Awadain, Ammar Saud Altowairqi, Nawaf Fawzan Alfawzan, Fatimah Mohammed Almazayen, Abdulrahman Jalwi Korkoman, Nawaf Saad Alrusayyis
IJMDC. 2020; 4(2): 429-434
» Abstract » doi: 10.24911/IJMDC.51-1576668182
Cited : 8 times [Click to see citing articles]

Population awareness about rheumatoid arthritis in Jazan region, Saudi Arabia
Ahmad Ali Hazzazi, Mohssen Hassen Ageeli, Ahmed Ali Muyidi, Abdulaziz Mohammad Abulgasim, Abdullah Ahmad Yateemi, Nabil Alhakami
IJMDC. 2020; 4(3): 668-675
» Abstract » doi: 10.24911/IJMDC.51-1576010943
Cited : 4 times [Click to see citing articles]

Prevalence and factors associated with depression among health care workers in National Guard Hospital in Riyadh, KSA
Noor Mohammad AlFahhad
IJMDC. 2018; 2(September 2018): 92-96
» Abstract » doi: 10.24911/IJMDC.51-1526306040
Cited : 4 times [Click to see citing articles]

About International Journal of Medicine in Developing Countries

Contact Information

How to cite this article