E-ISSN 1658-7820
 

Review Article
Online Published: 29 Dec 2024
 


Pulsed-field ablation versus standard thermal ablation in treatment of paroxysmal atrial fibrillation: a systematic review and meta-analysis

Rofayda Mansour Ahmad Mohamad, Turki Fahad Aldohan, Naif Abdullah Alzubidi, Faris Abdullah Abu Awwah, Rawiyah Abdulaziz Alessa, Maryam Ibrahim Aljohani, Rania Saad Alamri, Razan Shukr Alsheikh, Wedyan Hussain Alharbi, Ghadah Ali Alqarni, Ali Zain Abden Mohamed Alshammari.


Abstract
Pulsed field ablation (PFA) is a novel modality for atrial fibrillation (AF). This analysis compared the safety and efficacy of PFA versus standard thermal ablation (STA) in subjects with paroxysmal AF. A comprehensive exploration of electronic databases was adopted to identify trials in English, of human studies, from inception to 10th October 2024, and compared PFA to STA for paroxysmal AF. Pooled analyses were performed to assess treatment success, AF recurrence, adverse events, procedural time, and other secondary outcomes. Three studies (n = 1733) were included in the analysis. PFA demonstrated a significantly higher success rate than STA (OR = 1.29, 95% CI = [1.05-1.58], p = 0.02). There was no potential difference in AF recurrence, procedural time, or secondary outcomes. Pericardial complications and vascular access consequences were more common in the PFA subjects. PFA is an alternative to STA for paroxysmal AF treatment, offering a higher initial success rate and comparable long-term efficacy. However, the increased risk of pericardial complications and vascular access complications should be carefully considered. Further research is required to support such outcomes and to better understand the long-term outcomes of PFA.

Key words: pulsed-field ablation, standard thermal ablation, atrial fibrillation, meta-analysis, systemic review


 
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How to Cite this Article
Pubmed Style

Mohamad RMA, Aldohan TF, Alzubidi NA, Awwah FAA, Alessa RA, Aljohani MI, Alamri RS, Alsheikh RS, Alharbi WH, Alqarni GA, Alshammari AZAM. Pulsed-field ablation versus standard thermal ablation in treatment of paroxysmal atrial fibrillation: a systematic review and meta-analysis. IJMDC. 2024; 8(11): 3246-3255. doi:10.24911/IJMDC.51-1731654416


Web Style

Mohamad RMA, Aldohan TF, Alzubidi NA, Awwah FAA, Alessa RA, Aljohani MI, Alamri RS, Alsheikh RS, Alharbi WH, Alqarni GA, Alshammari AZAM. Pulsed-field ablation versus standard thermal ablation in treatment of paroxysmal atrial fibrillation: a systematic review and meta-analysis. https://www.ijmdc.com/?mno=228800 [Access: January 14, 2025]. doi:10.24911/IJMDC.51-1731654416


AMA (American Medical Association) Style

Mohamad RMA, Aldohan TF, Alzubidi NA, Awwah FAA, Alessa RA, Aljohani MI, Alamri RS, Alsheikh RS, Alharbi WH, Alqarni GA, Alshammari AZAM. Pulsed-field ablation versus standard thermal ablation in treatment of paroxysmal atrial fibrillation: a systematic review and meta-analysis. IJMDC. 2024; 8(11): 3246-3255. doi:10.24911/IJMDC.51-1731654416



Vancouver/ICMJE Style

Mohamad RMA, Aldohan TF, Alzubidi NA, Awwah FAA, Alessa RA, Aljohani MI, Alamri RS, Alsheikh RS, Alharbi WH, Alqarni GA, Alshammari AZAM. Pulsed-field ablation versus standard thermal ablation in treatment of paroxysmal atrial fibrillation: a systematic review and meta-analysis. IJMDC. (2024), [cited January 14, 2025]; 8(11): 3246-3255. doi:10.24911/IJMDC.51-1731654416



Harvard Style

Mohamad, R. M. A., Aldohan, . T. F., Alzubidi, . N. A., Awwah, . F. A. A., Alessa, . R. A., Aljohani, . M. I., Alamri, . R. S., Alsheikh, . R. S., Alharbi, . W. H., Alqarni, . G. A. & Alshammari, . A. Z. A. M. (2024) Pulsed-field ablation versus standard thermal ablation in treatment of paroxysmal atrial fibrillation: a systematic review and meta-analysis. IJMDC, 8 (11), 3246-3255. doi:10.24911/IJMDC.51-1731654416



Turabian Style

Mohamad, Rofayda Mansour Ahmad, Turki Fahad Aldohan, Naif Abdullah Alzubidi, Faris Abdullah Abu Awwah, Rawiyah Abdulaziz Alessa, Maryam Ibrahim Aljohani, Rania Saad Alamri, Razan Shukr Alsheikh, Wedyan Hussain Alharbi, Ghadah Ali Alqarni, and Ali Zain Abden Mohamed Alshammari. 2024. Pulsed-field ablation versus standard thermal ablation in treatment of paroxysmal atrial fibrillation: a systematic review and meta-analysis. International Journal of Medicine in Developing Countries, 8 (11), 3246-3255. doi:10.24911/IJMDC.51-1731654416



Chicago Style

Mohamad, Rofayda Mansour Ahmad, Turki Fahad Aldohan, Naif Abdullah Alzubidi, Faris Abdullah Abu Awwah, Rawiyah Abdulaziz Alessa, Maryam Ibrahim Aljohani, Rania Saad Alamri, Razan Shukr Alsheikh, Wedyan Hussain Alharbi, Ghadah Ali Alqarni, and Ali Zain Abden Mohamed Alshammari. "Pulsed-field ablation versus standard thermal ablation in treatment of paroxysmal atrial fibrillation: a systematic review and meta-analysis." International Journal of Medicine in Developing Countries 8 (2024), 3246-3255. doi:10.24911/IJMDC.51-1731654416



MLA (The Modern Language Association) Style

Mohamad, Rofayda Mansour Ahmad, Turki Fahad Aldohan, Naif Abdullah Alzubidi, Faris Abdullah Abu Awwah, Rawiyah Abdulaziz Alessa, Maryam Ibrahim Aljohani, Rania Saad Alamri, Razan Shukr Alsheikh, Wedyan Hussain Alharbi, Ghadah Ali Alqarni, and Ali Zain Abden Mohamed Alshammari. "Pulsed-field ablation versus standard thermal ablation in treatment of paroxysmal atrial fibrillation: a systematic review and meta-analysis." International Journal of Medicine in Developing Countries 8.11 (2024), 3246-3255. Print. doi:10.24911/IJMDC.51-1731654416



APA (American Psychological Association) Style

Mohamad, R. M. A., Aldohan, . T. F., Alzubidi, . N. A., Awwah, . F. A. A., Alessa, . R. A., Aljohani, . M. I., Alamri, . R. S., Alsheikh, . R. S., Alharbi, . W. H., Alqarni, . G. A. & Alshammari, . A. Z. A. M. (2024) Pulsed-field ablation versus standard thermal ablation in treatment of paroxysmal atrial fibrillation: a systematic review and meta-analysis. International Journal of Medicine in Developing Countries, 8 (11), 3246-3255. doi:10.24911/IJMDC.51-1731654416





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