E-ISSN 1658-7820
 

Review Article

Online Publishing Date: 17 / 01 / 2024

 


Prevalence and management outcomes of organophosphorus poisoning in emergency departments: systematic review

Nawaf Farhan Alrawili, Yasser Hamoud Mutlaq Alanazi, Mohammmed Mater Essa Sharahili, Emad Mohammed Hamad Hakami, Rehab Abdallah Alanazi, Nader Ali Alanazi, Talal Sharidah Alenezi, Eissa Zaedan M. Alenezi, Reham Muqbil Alanazi, Mohammed Farhan Alrowaili.


Abstract
Organophosphorus poisoning (OPP) is a significant public health concern in various regions, with its prevalence and outcomes influenced by diverse sociodemographic factors. This systematic review aimed to collate and analyze data from multiple studies to provide a comprehensive understanding of the prevalence, risk factors, and management outcomes of OPP in emergency departments. A systematic search was conducted in October 2023, adhering to the PRISMA guidelines, primarily using PubMed. Studies were selected based on specific inclusion and exclusion criteria, with a focus on those that investigated OPP prevalence and management outcomes in emergency departments. Out of 87 initial studies, 9 met the inclusion criteria, encompassing a total of 1,469 participants from countries like Nepal, India, Korea, China, and Turkey. The studies predominantly included the younger to middle-aged demographic, with a significant male representation indicating that young males. Key findings highlighted the role of pesticides, especially organophosphorus compounds, in intentional poisonings, which can be seen more in young and unmarried females. Additionally, the therapeutic efficacy of treatments like plasma exchange has proven to be another promising tool for management. Finally, the importance of specific prognostic indicators such as D-CRP and the sequential organ failure assessment (SOFA) score, when combined with lactate levels (SOFA-Lac), are superior predictors of mortality in patients with acute organophosphate pesticide poisoning. The insights from this review emphasize the need for targeted interventions, both therapeutic and preventive, to address the challenges posed by OPP, especially in high-risk populations.

Key words: Prevalence, management, outcomes, organophosphorus, poisoning.


 
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How to Cite this Article
Pubmed Style

Alrawili NF, Alanazi YHM, Sharahili MME, Hakami EMH, Alanazi RA, Alanazi NA, Alenezi TS, Alenezi EZM, Alanazi RM, Alrowaili MF. Prevalence and management outcomes of organophosphorus poisoning in emergency departments: systematic review. IJMDC. 2024; 8(2): 846-854. doi:10.24911/IJMDC.51-1701434074


Web Style

Alrawili NF, Alanazi YHM, Sharahili MME, Hakami EMH, Alanazi RA, Alanazi NA, Alenezi TS, Alenezi EZM, Alanazi RM, Alrowaili MF. Prevalence and management outcomes of organophosphorus poisoning in emergency departments: systematic review. https://www.ijmdc.com/?mno=179593 [Access: February 07, 2024]. doi:10.24911/IJMDC.51-1701434074


AMA (American Medical Association) Style

Alrawili NF, Alanazi YHM, Sharahili MME, Hakami EMH, Alanazi RA, Alanazi NA, Alenezi TS, Alenezi EZM, Alanazi RM, Alrowaili MF. Prevalence and management outcomes of organophosphorus poisoning in emergency departments: systematic review. IJMDC. 2024; 8(2): 846-854. doi:10.24911/IJMDC.51-1701434074



Vancouver/ICMJE Style

Alrawili NF, Alanazi YHM, Sharahili MME, Hakami EMH, Alanazi RA, Alanazi NA, Alenezi TS, Alenezi EZM, Alanazi RM, Alrowaili MF. Prevalence and management outcomes of organophosphorus poisoning in emergency departments: systematic review. IJMDC. (2024), [cited February 07, 2024]; 8(2): 846-854. doi:10.24911/IJMDC.51-1701434074



Harvard Style

Alrawili, N. F., Alanazi, . Y. H. M., Sharahili, . M. M. E., Hakami, . E. M. H., Alanazi, . R. A., Alanazi, . N. A., Alenezi, . T. S., Alenezi, . E. Z. M., Alanazi, . R. M. & Alrowaili, . M. F. (2024) Prevalence and management outcomes of organophosphorus poisoning in emergency departments: systematic review. IJMDC, 8 (2), 846-854. doi:10.24911/IJMDC.51-1701434074



Turabian Style

Alrawili, Nawaf Farhan, Yasser Hamoud Mutlaq Alanazi, Mohammmed Mater Essa Sharahili, Emad Mohammed Hamad Hakami, Rehab Abdallah Alanazi, Nader Ali Alanazi, Talal Sharidah Alenezi, Eissa Zaedan M. Alenezi, Reham Muqbil Alanazi, and Mohammed Farhan Alrowaili. 2024. Prevalence and management outcomes of organophosphorus poisoning in emergency departments: systematic review. International Journal of Medicine in Developing Countries, 8 (2), 846-854. doi:10.24911/IJMDC.51-1701434074



Chicago Style

Alrawili, Nawaf Farhan, Yasser Hamoud Mutlaq Alanazi, Mohammmed Mater Essa Sharahili, Emad Mohammed Hamad Hakami, Rehab Abdallah Alanazi, Nader Ali Alanazi, Talal Sharidah Alenezi, Eissa Zaedan M. Alenezi, Reham Muqbil Alanazi, and Mohammed Farhan Alrowaili. "Prevalence and management outcomes of organophosphorus poisoning in emergency departments: systematic review." International Journal of Medicine in Developing Countries 8 (2024), 846-854. doi:10.24911/IJMDC.51-1701434074



MLA (The Modern Language Association) Style

Alrawili, Nawaf Farhan, Yasser Hamoud Mutlaq Alanazi, Mohammmed Mater Essa Sharahili, Emad Mohammed Hamad Hakami, Rehab Abdallah Alanazi, Nader Ali Alanazi, Talal Sharidah Alenezi, Eissa Zaedan M. Alenezi, Reham Muqbil Alanazi, and Mohammed Farhan Alrowaili. "Prevalence and management outcomes of organophosphorus poisoning in emergency departments: systematic review." International Journal of Medicine in Developing Countries 8.2 (2024), 846-854. Print. doi:10.24911/IJMDC.51-1701434074



APA (American Psychological Association) Style

Alrawili, N. F., Alanazi, . Y. H. M., Sharahili, . M. M. E., Hakami, . E. M. H., Alanazi, . R. A., Alanazi, . N. A., Alenezi, . T. S., Alenezi, . E. Z. M., Alanazi, . R. M. & Alrowaili, . M. F. (2024) Prevalence and management outcomes of organophosphorus poisoning in emergency departments: systematic review. International Journal of Medicine in Developing Countries, 8 (2), 846-854. doi:10.24911/IJMDC.51-1701434074





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