Original Article
IJMDC. 2023; 7(4): 672-675
Association between time to anticoagulant administration and the outcome of patients with acute coronary syndrome
Authors: Abdullah Bakhsh, Turki Alharbi, Randa Abushanab, Shahad Alabsi, Esraa Basalem, Sahar Alsifri, Asail Almukhles, Lina Sharaf, Maysam Aljahdali.
ABSTRACT
Objective: This study aimed to determine the association between the time of anticoagulant administration and the outcome of patients with the acute coronary syndrome (ACS). Methods: This was a single-center retrospective cohort study of adult patients diagnosed with ACS in the emergency department at King Abdul-Aziz University Hospital (KAUH) in Jeddah between January 2015 and December 2020. The data were obtained from the medical records of the KAUH, and through Google forms. Result: Of 206 patients, using a cutoff of 4 hours, 55 patients (26.5%) were classified into the early treatment group, whereas 152 patients (73.4%) were in the non-early treatment (>4 hours) group. In the final analysis, the non-early treatment group had a higher mortality rate compared with the early treatment group (4.6% vs. 3.6%, p < 0.01) but had a lower risk for intracranial bleeding compared with the early treatment group (0% vs. 1.8%, p < 0.01). Conclusion: It was demonstrated that lower rates of mortality were correlated with the early administration of treatment in ACS. A 3.6% mortality rate had declined in patients who received early treatment in comparison with the 4.6% mortality rate in patients who had not received treatment early. This emphasizes how early therapy is effective and essential in enchasing and improving quality and overall patient health and life. Thereby, motivating early interventions in hospitals.
Keywords:
acute coronary syndrome, anticoagulant therapy, mortality, ST segment elevation myocardial infarction, timing
Authors
Abdullah Bakhsh
Department of Emergency Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
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Turki Alharbi
Department of Emergency Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
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Randa Abushanab
Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
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Shahad Alabsi
Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
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Esraa Basalem
Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
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Sahar Alsifri
Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
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Asail Almukhles
Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
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Lina Sharaf
Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia
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Maysam Aljahdali
Faculty of Medicine, King Abdulaziz University Hospital, Jeddah, Saudi Arabia.
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Correspondence to:
. Randa Abushanab, Faculty of medicine, King Abdulaziz University Hospital, Jeddah, SAU.; randa.h.abushanab@gmail.com
Publication history
Received 02 Jan 2023
Accepted 03 Jan 2023
Published online 04 Jan 2023
Published in print 15 Jan 2023
How to cite this article?
Export to EndNote Export to refManPubmed Style
Bakhsh A, Alharbi T, Abushanab R, Alabsi S, Basalem E, Alsifri S, Almukhles A, Sharaf L, Aljahdali M. Association between time to anticoagulant administration and the outcome of patients with acute coronary syndrome. IJMDC. 2023; 7(4): 672-675. doi:10.24911/IJMDC.51-1672244478
Web Style
Bakhsh A, Alharbi T, Abushanab R, Alabsi S, Basalem E, Alsifri S, Almukhles A, Sharaf L, Aljahdali M. Association between time to anticoagulant administration and the outcome of patients with acute coronary syndrome. https://www.ijmdc.com/?mno=134740 [Access: March 22, 2023]. doi:10.24911/IJMDC.51-1672244478
AMA (American Medical Association) Style
Bakhsh A, Alharbi T, Abushanab R, Alabsi S, Basalem E, Alsifri S, Almukhles A, Sharaf L, Aljahdali M. Association between time to anticoagulant administration and the outcome of patients with acute coronary syndrome. IJMDC. 2023; 7(4): 672-675. doi:10.24911/IJMDC.51-1672244478
Vancouver/ICMJE Style
Bakhsh A, Alharbi T, Abushanab R, Alabsi S, Basalem E, Alsifri S, Almukhles A, Sharaf L, Aljahdali M. Association between time to anticoagulant administration and the outcome of patients with acute coronary syndrome. IJMDC. (2023), [cited March 22, 2023]; 7(4): 672-675. doi:10.24911/IJMDC.51-1672244478
Harvard Style
Bakhsh, A., Alharbi, . T., Abushanab, . R., Alabsi, . S., Basalem, . E., Alsifri, . S., Almukhles, . A., Sharaf, . L. & Aljahdali, . M. (2023) Association between time to anticoagulant administration and the outcome of patients with acute coronary syndrome. IJMDC, 7 (4), 672-675. doi:10.24911/IJMDC.51-1672244478
Turabian Style
Bakhsh, Abdullah, Turki Alharbi, Randa Abushanab, Shahad Alabsi, Esraa Basalem, Sahar Alsifri, Asail Almukhles, Lina Sharaf, and Maysam Aljahdali. 2023. Association between time to anticoagulant administration and the outcome of patients with acute coronary syndrome. International Journal of Medicine in Developing Countries, 7 (4), 672-675. doi:10.24911/IJMDC.51-1672244478
Chicago Style
Bakhsh, Abdullah, Turki Alharbi, Randa Abushanab, Shahad Alabsi, Esraa Basalem, Sahar Alsifri, Asail Almukhles, Lina Sharaf, and Maysam Aljahdali. "Association between time to anticoagulant administration and the outcome of patients with acute coronary syndrome." International Journal of Medicine in Developing Countries 7 (2023), 672-675. doi:10.24911/IJMDC.51-1672244478
MLA (The Modern Language Association) Style
Bakhsh, Abdullah, Turki Alharbi, Randa Abushanab, Shahad Alabsi, Esraa Basalem, Sahar Alsifri, Asail Almukhles, Lina Sharaf, and Maysam Aljahdali. "Association between time to anticoagulant administration and the outcome of patients with acute coronary syndrome." International Journal of Medicine in Developing Countries 7.4 (2023), 672-675. Print. doi:10.24911/IJMDC.51-1672244478
APA (American Psychological Association) Style
Bakhsh, A., Alharbi, . T., Abushanab, . R., Alabsi, . S., Basalem, . E., Alsifri, . S., Almukhles, . A., Sharaf, . L. & Aljahdali, . M. (2023) Association between time to anticoagulant administration and the outcome of patients with acute coronary syndrome. International Journal of Medicine in Developing Countries, 7 (4), 672-675. doi:10.24911/IJMDC.51-1672244478
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