Original Article

IJMDC. 2020; 4(11): 1766-1770

Development and validation of a questionnaire measuring the awareness of Isotretinoinís teratogenic effects among women in Makkah province, Saudi Arabia

Authors: Louai A. Salah, Yara R. Elhaddad, Rawan Al-Mekhlafi, Rawabi Attiyah, Daniah Ahmed.

ABSTRACT

Background: Isotretinoin, an oral vitamin A analog, is the most effective acne medication. Unfortunately, such potency comes with various side effects. This study was carried out for the development and validation of a self-administered online questionnaire on isotretinoin teratogenicity awareness among women in Makkah Province, Saudi Arabia. Methodology: A 28-item validated self-administered online questionnaire was used in this study, from January 27, 2019 to February 25, 2020. Two pilot surveys were carried out to test the validity of the modified questionnaire, and Cronbachís alpha was found to be 0.742. The pilot surveys only included women of childbearing age (12-51 years old) in addition to being on isotretinoin treatment. Results: Out of the total 24 responses, 22 women experienced skin, lip, and eye dryness, four experienced increased blood cholesterol level, and two did not face any side effects at all. Five patients were sexually active and 18 were not sexually active during the isotretinoin course. Higher awareness was seen for both the teratogenicity and avoidance of pregnancy aspects in the sexually active group when compared with the non-sexually active group. Conclusion: Educating patients on proper practices should be prioritized. Overall, the questionnaire has been proven valid and reliable to be used on large-scale studies in the population of interest.

Keywords:
Acne, female, perception, pregnancy, Saudi Arabia, survey


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Development and validation of a questionnaire measuring the awareness of Isotretinoinís teratogenic effects among women in Makkah province, Saudi Arabia


Authors
Louai A Salah
East Jeddah General Hospital, Ministry of Health, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Yara R Elhaddad
Batterjee Medical College, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Rawan Al-Mekhlafi
Batterjee Medical College, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Rawabi Attiyah
Batterjee Medical College, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Daniah Ahmed
Batterjee Medical College, Jeddah, Saudi Arabia.
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Correspondence to:
. Louai A. Salah, East Jeddah General Hospital, Ministry of Health, Jeddah, Saudi Arabia.; loai.salah@gmail.com

Publication history
Received 27 Aug 2020
Accepted 27 Sep 2020
Published online 28 Oct 2020
Published in print 05 Nov 2020

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Pubmed Style

Salah LA, Elhaddad YR, Al-Mekhlafi R, Attiyah R, Ahmed D. Development and validation of a questionnaire measuring the awareness of Isotretinoinís teratogenic effects among women in Makkah province, Saudi Arabia. IJMDC. 2020; 4(11): 1766-1770. doi:10.24911/IJMDC.51-1598445099


Web Style

Salah LA, Elhaddad YR, Al-Mekhlafi R, Attiyah R, Ahmed D. Development and validation of a questionnaire measuring the awareness of Isotretinoinís teratogenic effects among women in Makkah province, Saudi Arabia. http://www.ijmdc.com/?mno=129023 [Access: January 24, 2021]. doi:10.24911/IJMDC.51-1598445099


AMA (American Medical Association) Style

Salah LA, Elhaddad YR, Al-Mekhlafi R, Attiyah R, Ahmed D. Development and validation of a questionnaire measuring the awareness of Isotretinoinís teratogenic effects among women in Makkah province, Saudi Arabia. IJMDC. 2020; 4(11): 1766-1770. doi:10.24911/IJMDC.51-1598445099


Vancouver/ICMJE Style

Salah LA, Elhaddad YR, Al-Mekhlafi R, Attiyah R, Ahmed D. Development and validation of a questionnaire measuring the awareness of Isotretinoinís teratogenic effects among women in Makkah province, Saudi Arabia. IJMDC. (2020), [cited January 24, 2021]; 4(11): 1766-1770. doi:10.24911/IJMDC.51-1598445099


Harvard Style

Salah, L. A., Elhaddad, . Y. R., Al-Mekhlafi, . R., Attiyah, . R. & Ahmed, . D. (2020) Development and validation of a questionnaire measuring the awareness of Isotretinoinís teratogenic effects among women in Makkah province, Saudi Arabia. IJMDC, 4 (11), 1766-1770. doi:10.24911/IJMDC.51-1598445099


Turabian Style

Salah, Louai A., Yara R. Elhaddad, Rawan Al-Mekhlafi, Rawabi Attiyah, and Daniah Ahmed. 2020. Development and validation of a questionnaire measuring the awareness of Isotretinoinís teratogenic effects among women in Makkah province, Saudi Arabia. International Journal of Medicine in Developing Countries, 4 (11), 1766-1770. doi:10.24911/IJMDC.51-1598445099


Chicago Style

Salah, Louai A., Yara R. Elhaddad, Rawan Al-Mekhlafi, Rawabi Attiyah, and Daniah Ahmed. "Development and validation of a questionnaire measuring the awareness of Isotretinoinís teratogenic effects among women in Makkah province, Saudi Arabia." International Journal of Medicine in Developing Countries 4 (2020), 1766-1770. doi:10.24911/IJMDC.51-1598445099


MLA (The Modern Language Association) Style

Salah, Louai A., Yara R. Elhaddad, Rawan Al-Mekhlafi, Rawabi Attiyah, and Daniah Ahmed. "Development and validation of a questionnaire measuring the awareness of Isotretinoinís teratogenic effects among women in Makkah province, Saudi Arabia." International Journal of Medicine in Developing Countries 4.11 (2020), 1766-1770. Print. doi:10.24911/IJMDC.51-1598445099


APA (American Psychological Association) Style

Salah, L. A., Elhaddad, . Y. R., Al-Mekhlafi, . R., Attiyah, . R. & Ahmed, . D. (2020) Development and validation of a questionnaire measuring the awareness of Isotretinoinís teratogenic effects among women in Makkah province, Saudi Arabia. International Journal of Medicine in Developing Countries, 4 (11), 1766-1770. doi:10.24911/IJMDC.51-1598445099


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