E-ISSN 1658-7820
 
2024, Vol: 8, Issue: 4
8 / 4Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article

Online Publishing Date:
24 / 09 / 2021

 


Knowledge and attitude of acetaminophen induced hepatotoxicity. A community-based study in Al-Madinah Al-Munawwarah

Inas Abdullah Barakat, Shahd Ateeg Alrehaili, Khawlah Sultan Alhussain, Reem Mustafa Andijany, Rana Mustafa Andijany, Ayat Atallah Alsamiri.


Abstract
Background: Acetaminophen is widely used as an antipyretic and analgesic. It is considered safe when administered within its therapeutic range with a maximum daily dose (MDD) of 4,000 mg/day. In cases of acute intoxication, complications such as acute liver failure can occur. This study aims to assess the knowledge and attitudes toward acetaminophen-induced hepatotoxicity among the adult population in Al-Madinah Al-Munawwarah, Saudi Arabia.
Methods: This descriptive cross-sectional study was conducted among adults (above 18 years) living in Al-Madinah Al-Munawwarah, Saudi Arabia, performed via an electronically distributed questionnaire using social media in March 2020.
Results: Of 405 participants, only 15.3% recognized 4,000 mg/day acetaminophen to be the MDD. Meanwhile, 84% of participants knew of liver damage being a side-effect of acetaminophen. Panadol was identified as a drug containing acetaminophen by 60% of participants. Regarding attitude, 30.1% of participants revealed that they look for acetaminophen as an ingredient before buying over-the-counter medications, while 22.7% look for it in medicines prescribed by their physicians. Only 24.7% of the participants reported receiving information about acetaminophen from health care workers, most of which were from doctors (55%). Panadol and Fevadol were the most used medications with a frequency of once-twice daily.
Conclusion: According to the study results, there is a lack of awareness regarding acetaminophen’s MDD. However, awareness of acetaminophen-induced hepatotoxicity is satisfactory among the Al-Madinah Al-Munawwarah population.

Key words: Acetaminophen, acute liver failure, hepatotoxicity, over the counter medications.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Inas Abdullah Barakat
Articles by Shahd Ateeg Alrehaili
Articles by Khawlah Sultan Alhussain
Articles by Reem Mustafa Andijany
Articles by Rana Mustafa Andijany
Articles by Ayat Atallah Alsamiri
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Barakat IA, Alrehaili SA, Alhussain KS, Andijany RM, Andijany RM, Alsamiri AA. Knowledge and attitude of acetaminophen induced hepatotoxicity. A community-based study in Al-Madinah Al-Munawwarah. IJMDC. 2021; 5(10): 1695-1709. doi:10.24911/IJMDC.51-1624220380

Web Style

Barakat IA, Alrehaili SA, Alhussain KS, Andijany RM, Andijany RM, Alsamiri AA. Knowledge and attitude of acetaminophen induced hepatotoxicity. A community-based study in Al-Madinah Al-Munawwarah. https://www.ijmdc.com/?mno=89455 [Access: March 26, 2024]. doi:10.24911/IJMDC.51-1624220380

AMA (American Medical Association) Style

Barakat IA, Alrehaili SA, Alhussain KS, Andijany RM, Andijany RM, Alsamiri AA. Knowledge and attitude of acetaminophen induced hepatotoxicity. A community-based study in Al-Madinah Al-Munawwarah. IJMDC. 2021; 5(10): 1695-1709. doi:10.24911/IJMDC.51-1624220380


Vancouver/ICMJE Style

Barakat IA, Alrehaili SA, Alhussain KS, Andijany RM, Andijany RM, Alsamiri AA. Knowledge and attitude of acetaminophen induced hepatotoxicity. A community-based study in Al-Madinah Al-Munawwarah. IJMDC. (2021), [cited March 26, 2024]; 5(10): 1695-1709. doi:10.24911/IJMDC.51-1624220380


Harvard Style

Barakat, I. A., Alrehaili, . S. A., Alhussain, . K. S., Andijany, . R. M., Andijany, . R. M. & Alsamiri, . A. A. (2021) Knowledge and attitude of acetaminophen induced hepatotoxicity. A community-based study in Al-Madinah Al-Munawwarah. IJMDC, 5 (10), 1695-1709. doi:10.24911/IJMDC.51-1624220380


Turabian Style

Barakat, Inas Abdullah, Shahd Ateeg Alrehaili, Khawlah Sultan Alhussain, Reem Mustafa Andijany, Rana Mustafa Andijany, and Ayat Atallah Alsamiri. 2021. Knowledge and attitude of acetaminophen induced hepatotoxicity. A community-based study in Al-Madinah Al-Munawwarah. International Journal of Medicine in Developing Countries, 5 (10), 1695-1709. doi:10.24911/IJMDC.51-1624220380


Chicago Style

Barakat, Inas Abdullah, Shahd Ateeg Alrehaili, Khawlah Sultan Alhussain, Reem Mustafa Andijany, Rana Mustafa Andijany, and Ayat Atallah Alsamiri. "Knowledge and attitude of acetaminophen induced hepatotoxicity. A community-based study in Al-Madinah Al-Munawwarah." International Journal of Medicine in Developing Countries 5 (2021), 1695-1709. doi:10.24911/IJMDC.51-1624220380


MLA (The Modern Language Association) Style

Barakat, Inas Abdullah, Shahd Ateeg Alrehaili, Khawlah Sultan Alhussain, Reem Mustafa Andijany, Rana Mustafa Andijany, and Ayat Atallah Alsamiri. "Knowledge and attitude of acetaminophen induced hepatotoxicity. A community-based study in Al-Madinah Al-Munawwarah." International Journal of Medicine in Developing Countries 5.10 (2021), 1695-1709. Print. doi:10.24911/IJMDC.51-1624220380


APA (American Psychological Association) Style

Barakat, I. A., Alrehaili, . S. A., Alhussain, . K. S., Andijany, . R. M., Andijany, . R. M. & Alsamiri, . A. A. (2021) Knowledge and attitude of acetaminophen induced hepatotoxicity. A community-based study in Al-Madinah Al-Munawwarah. International Journal of Medicine in Developing Countries, 5 (10), 1695-1709. doi:10.24911/IJMDC.51-1624220380




Most Viewed Articles
Most Accessed Articles

  • Marginal adaptation of fixed prosthodontics
    Shahad Mohammed Halawani, Sahar Amer Al-Harbi
    IJMDC. 2017; 1(2): 78-84
    » Abstract » doi: 10.24911/IJMDC.1.2.7

  • Parasites in central nervous system
    Amal Ahmed Mohamed, Asmaa Mohamed Mansour
    IJMDC. 2017; 1(2): 72-77
    » Abstract » doi: 10.24911/IJMDC.1.2.6

  • Non-diabetic retinopathy: a case report
    Hassan F. Alkwikbi, Nabil Mamon Abdelfattah, Haithem Mamon Abdelfattah
    IJMDC. 2017; 1(1): 33-37
    » Abstract » doi: 10.24911/IJMDC.1.1.6

  • Vitamin D deficiency among high school female students in Riyadh
    Sahar Mohsen Aldhafeeri, Fatemah Ibraheem Alrawaji, Abrar Mubarak Algharbi, Alanoud Abdullah Alhessan, Ayat Sami Qabaja, Ghaleah Abdulaziz Alnassar, Ghaliah Ofayn Alsulami, Mashael Belal Alrubaian, Norah Abdulaziz Alhatim, Salehah Salih Alotaibi, Zahra Ali Alkhamees
    IJMDC. 2017; 1(1): 18-23
    » Abstract » doi: 10.24911/IJMDC.1.1.4

  • Prognosis of chronic complications of diabetes mellitus (DM) after multiple events of diabetic ketoacidosis (DKA)
    Baraa Faiez Rajab, Anwar Essa Alamrim, Ali Essa Alamri
    IJMDC. 2019; 3(5): 474-479
    » Abstract » doi: 10.24911/IJMDC.51-1546551993

    •
    Most Downloaded
    Top Downloaded Articles

  • Anti-IL-17 markedly inhibited the in vitro granuloma induced by Schistosoma mansoni soluble egg antigen.
    Asmaa Ezz, Irene S. Gmail, Fatma Elzahraa H. Salem, Rabab Salama, Soad Nady
    IJMDC. 2018; 2(January 2018): 38-46
    » Abstract » doi: 10.24911/IJMDC.2.1.7

  • Vitamin D deficiency among high school female students in Riyadh
    Sahar Mohsen Aldhafeeri, Fatemah Ibraheem Alrawaji, Abrar Mubarak Algharbi, Alanoud Abdullah Alhessan, Ayat Sami Qabaja, Ghaleah Abdulaziz Alnassar, Ghaliah Ofayn Alsulami, Mashael Belal Alrubaian, Norah Abdulaziz Alhatim, Salehah Salih Alotaibi, Zahra Ali Alkhamees
    IJMDC. 2017; 1(1): 18-23
    » Abstract » doi: 10.24911/IJMDC.1.1.4

  • Antibiotic Resistance Crisis
    Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
    IJMDC. 2019; 3(6): 561-564
    » Abstract » doi: 10.24911/IJMDC.51-1549060699

  • The knowledge of mothers about children malnutrition and associated factors
    Anas Abdulrahman Aljohani, Mujahid Abdulrahman Aljohani
    IJMDC. 2020; 4(1): 7-11
    » Abstract » doi: 10.24911/IJMDC.51-1541620358

  • Knowledge and attitude of caregivers of cerebral palsy children in Riyadh city
    Abdulaziz Alruwaished, Baleegh Ali, Lubna Abdullah Alhowaimil , Abaraa adullah Alhowaimil, Najd Abdullah Alhowaimil, Aminah Alessa
    IJMDC. 2020; 4(1): 12-17
    » Abstract » doi: 10.24911/IJMDC.51-1547833051

    •
    Most Cited Articles
    Most Cited Articles

  • Antibiotic Resistance Crisis
    Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
    IJMDC. 2019; 3(6): 561-564
    » Abstract » doi: 10.24911/IJMDC.51-1549060699
    Cited : 34 times [Click to see citing articles]

  • Prevalence of depression, anxiety and stress among diabetes mellitus patients in Arar, Northern Saudi Arabia
    AMohammed Elamin Mukrim, Nujud Muteb D. Alshammari, Wurud Muteb D. Alshammari, Maali Subhi T. Alshammari, Yousef Nasif R. Alshammari, Abdulaziz Sael M. Alshammari, Maisa Hamad F. Alanazi, Abdulelah Abdulrhman F. Alzammam, Muharib Mana M. Alshammari, Slwa Khaled Abu Asyah, Aseel Jamal Alzuhayri, Mushref Saeid Alshammari
    IJMDC. 2019; 3(3): 229-233
    » Abstract » doi: 10.24911/IJMDC.51-1542576396
    Cited : 8 times [Click to see citing articles]

  • Knowledge, attitude, and practice of breast self-examination toward breast cancer among female students at King Saud University in Riyadh, Saudi Arabia
    Abdullah Nasser Alomair, Dania Ghazi Felemban, Mohannad Sami Felemban, Jameel Abdullah Awadain, Ammar Saud Altowairqi, Nawaf Fawzan Alfawzan, Fatimah Mohammed Almazayen, Abdulrahman Jalwi Korkoman, Nawaf Saad Alrusayyis
    IJMDC. 2020; 4(2): 429-434
    » Abstract » doi: 10.24911/IJMDC.51-1576668182
    Cited : 8 times [Click to see citing articles]

  • Population awareness about rheumatoid arthritis in Jazan region, Saudi Arabia
    Ahmad Ali Hazzazi, Mohssen Hassen Ageeli, Ahmed Ali Muyidi, Abdulaziz Mohammad Abulgasim, Abdullah Ahmad Yateemi, Nabil Alhakami
    IJMDC. 2020; 4(3): 668-675
    » Abstract » doi: 10.24911/IJMDC.51-1576010943
    Cited : 4 times [Click to see citing articles]

  • Prevalence and factors associated with depression among health care workers in National Guard Hospital in Riyadh, KSA
    Noor Mohammad AlFahhad
    IJMDC. 2018; 2(September 2018): 92-96
    » Abstract » doi: 10.24911/IJMDC.51-1526306040
    Cited : 4 times [Click to see citing articles]

    •

    About International Journal of Medicine in Developing Countries

    International Journal of Medicine in Developing Countries is a peer-reviewed, open access international medical journal. Journal Title Internat ... Read more.



    For best results, please use Internet Explorer or Google Chrome.

    Contact Information

    Publisher: Discover STM Publishing Ltd. 164 Moyville. Rathfarnham, Dublin, D16Y4E, Ireland

    Hours:  M-F: 7:30am - 4:30pm 

    Fax: +353 (0)1 633 5037 

    Emails:

    Journal Editorial Office:  contact@ijmdc.com

    All queries regarding the publishing or accepting of the manuscript should be directed to the Journal Editorial Office at Riyadh, Saudi Arabia. 

    Publishing and Hosting service is provided by Discover STM (Ireland):  contact@discoverpublish.com
    POLICIES & JOURNAL LINKS
    Author Login
    Reviewer Login
    About Publisher
    Advertising Policy
    Author's Rights and Obligations
    Conflict of Interest Policy
    Copyright Information
    Digital Archiving & Preservation Policies
    Editorial Policies
    Peer Review Policy
    Editorial & Peer Review Process
    License Information
    Open Access Policy
    Plagiarism Policy
    Privacy Policy
    Protection of Research Participants (Statement On Human And Animal Rights)
    Publication Ethics and Publication Malpractice Statement
    Corrections, Retractions & Expressions of Concern
    Self-Archiving Policies
    Statement of Informed Consent
    Terms of Use