E-ISSN 1658-7820
 

Original Article

Online Publishing Date:
02 / 07 / 2021

 


The effect of single dose Methotrexate in the treatment of scar ectopic pregnancy

Haifa Faisal Lardhi.


Abstract
Background: Cesarean scar ectopic pregnancy is a novel and rare disease that is increasing across the globe at a threatening rate. Thus, this study aimed to assess the effect of a single dose of methotrexate (MTX) to treat the scar ectopic pregnancy (SEP) and to compare its effects with the treatment by multiple doses of MTX.
Methods: A retrospective cohort study was conducted in Security Forces Hospital in Riyadh, Saudi Arabia from 2016 to 2020. The study included 13 pregnant women with history of cesarean section, diagnosed by official pelvic ultrasound or pelvic magnetic resonance imaging with SEP. Participants were sampled using a convenient non-probability sampling technique and data were collected via phone interviews.
Results: In the selected cohort, around 10 (76.9%) women reported a complete and uncomplicated resolution within a few months with a single dose of MTX, whereas, three women (23.1%) were successfully treated with multiple doses of MTX. However, seven (53.8%) had symptoms after taking MTX (which included vaginal bleeding, pain, fever, headache, diarrhea, low mood, and stomatitis), where the other six (46.2%) had no symptoms. For all participants, the level of beta human chorionic gonadotropin became normal after an average of 61 days from administration of MTX and six (46.2%) of them conceived with normal pregnancy.
Conclusion: MTX therapy seems to be an effective and safe approach for SEP treatment, especially in women who want to conceive successfully.

Key words: Cesarean scar pregnancy, ectopic pregnancy, methotrexate, scar ectopic


 
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Pubmed Style

Haifa Faisal Lardhi. The effect of single dose Methotrexate in the treatment of scar ectopic pregnancy. IJMDC. 2021; 5(7): 1417-1421. doi:10.24911/IJMDC.51-1622213060


Web Style

Haifa Faisal Lardhi. The effect of single dose Methotrexate in the treatment of scar ectopic pregnancy. https://www.ijmdc.com/?mno=84415 [Access: March 27, 2024]. doi:10.24911/IJMDC.51-1622213060


AMA (American Medical Association) Style

Haifa Faisal Lardhi. The effect of single dose Methotrexate in the treatment of scar ectopic pregnancy. IJMDC. 2021; 5(7): 1417-1421. doi:10.24911/IJMDC.51-1622213060



Vancouver/ICMJE Style

Haifa Faisal Lardhi. The effect of single dose Methotrexate in the treatment of scar ectopic pregnancy. IJMDC. (2021), [cited March 27, 2024]; 5(7): 1417-1421. doi:10.24911/IJMDC.51-1622213060



Harvard Style

Haifa Faisal Lardhi (2021) The effect of single dose Methotrexate in the treatment of scar ectopic pregnancy. IJMDC, 5 (7), 1417-1421. doi:10.24911/IJMDC.51-1622213060



Turabian Style

Haifa Faisal Lardhi. 2021. The effect of single dose Methotrexate in the treatment of scar ectopic pregnancy. International Journal of Medicine in Developing Countries, 5 (7), 1417-1421. doi:10.24911/IJMDC.51-1622213060



Chicago Style

Haifa Faisal Lardhi. "The effect of single dose Methotrexate in the treatment of scar ectopic pregnancy." International Journal of Medicine in Developing Countries 5 (2021), 1417-1421. doi:10.24911/IJMDC.51-1622213060



MLA (The Modern Language Association) Style

Haifa Faisal Lardhi. "The effect of single dose Methotrexate in the treatment of scar ectopic pregnancy." International Journal of Medicine in Developing Countries 5.7 (2021), 1417-1421. Print. doi:10.24911/IJMDC.51-1622213060



APA (American Psychological Association) Style

Haifa Faisal Lardhi (2021) The effect of single dose Methotrexate in the treatment of scar ectopic pregnancy. International Journal of Medicine in Developing Countries, 5 (7), 1417-1421. doi:10.24911/IJMDC.51-1622213060





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