IJMDC. 2021; 5(3): 968-973

Treatment of resistant urinary tract infection: a systematic review

Authors: Saleh Ahmed Alammari, Abdullah Radhyan A. AlRuwaili, Abdulaziz Abdullah Almutairi, Adeeb Naif Mhaileb Alshammari.

ABSTRACT

Background: Urinary tract infection (UTI) is frequent among both genders and in different age groups. However, the incidence of resistant infections is increasing, especially with the increased incidence of antimicrobial abuse. Furthermore, treatment options for these resistant infections are scarce, and their efficacy is controversial. This systematic review will demonstrate the management options and strategies for resistant UTI in different age groups among males and females over the last 10 years. Method: The research team searched the medical literature via four databases, which were Medline, PubMed, Embase, and SCOPUS. The databases were searched with filters for English articles and publication dates between 2011 and 2021. The search keywords were “management” OR “treatment” AND “urinary tract infection” OR “UTI” AND “resistant” AND “antibiotics”. The next stage was revising the results to comprise original research studies that evaluated different regimens for the management of resistant UTIs. All the included studies mentioned the type of medication used for treatment and the type of resistant bacterial strain that caused the UTI. Result: A total of 98 articles were retrieved. After filtering review articles and selecting original research studies solely, 12 articles were obtained. Eight research studies were eligible. Seven studies had a retrospective design. Fosfomycin was the most frequently tested antibiotic, as a monotherapy or in combination with either aminoglycoside or carbapenem. The most frequently identified strains were Escherichia coli and Klebsiella pneumoniae. Some studies also examined Pseudomonas aeruginosa and other Gram-negative bacilli. Conclusion: Fosfomycin shows promising efficacy and safety profile against multidrug-resistant bacterial strains causing UTI. Further prospective studies on other antibiotic combinations are mandatory.

Keywords:
Urinary tract infection, resistant, bacteria, antibiotics.


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Treatment of resistant urinary tract infection: a systematic review


Authors
Saleh Ahmed Alammari
Medical Intern, University of Hail, Hail, Saudi Arabia
PubMed articlesGoogle scholar articles

Abdullah Radhyan A AlRuwaili
Medical Intern, University of Aljouf, Aljouf, Saudi Arabia
PubMed articlesGoogle scholar articles

Abdulaziz Abdullah Almutairi
Medical Intern, Majmaah University, Majmaah, Saudi Arabia
PubMed articlesGoogle scholar articles

Adeeb Naif Mhaileb Alshammari
Medical Intern, University of Hail, Hail, Saudi Arabia.
PubMed articlesGoogle scholar articles


Correspondence to:
. Saleh Ahmed Alammari, Medical Intern, University of Hail, Hail, Saudi Arabia.; s201407637@hotmail.com

Publication history
Received 31 Jan 2021
Accepted 10 Feb 2021
Published online 01 Mar 2021
Published in print 04 Mar 2021

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Pubmed Style

Alammari SA, AlRuwaili ARA, Almutairi AA, Alshammari ANM. Treatment of resistant urinary tract infection: a systematic review. IJMDC. 2021; 5(3): 968-973. doi:10.24911/IJMDC.51-1612133177


Web Style

Alammari SA, AlRuwaili ARA, Almutairi AA, Alshammari ANM. Treatment of resistant urinary tract infection: a systematic review. http://www.ijmdc.com/?mno=50916 [Access: April 22, 2021]. doi:10.24911/IJMDC.51-1612133177


AMA (American Medical Association) Style

Alammari SA, AlRuwaili ARA, Almutairi AA, Alshammari ANM. Treatment of resistant urinary tract infection: a systematic review. IJMDC. 2021; 5(3): 968-973. doi:10.24911/IJMDC.51-1612133177


Vancouver/ICMJE Style

Alammari SA, AlRuwaili ARA, Almutairi AA, Alshammari ANM. Treatment of resistant urinary tract infection: a systematic review. IJMDC. (2021), [cited April 22, 2021]; 5(3): 968-973. doi:10.24911/IJMDC.51-1612133177


Harvard Style

Alammari, S. A., AlRuwaili, . A. R. A., Almutairi, . A. A. & Alshammari, . A. N. M. (2021) Treatment of resistant urinary tract infection: a systematic review. IJMDC, 5 (3), 968-973. doi:10.24911/IJMDC.51-1612133177


Turabian Style

Alammari, Saleh Ahmed, Abdullah Radhyan A. AlRuwaili, Abdulaziz Abdullah Almutairi, and Adeeb Naif Mhaileb Alshammari. 2021. Treatment of resistant urinary tract infection: a systematic review. International Journal of Medicine in Developing Countries, 5 (3), 968-973. doi:10.24911/IJMDC.51-1612133177


Chicago Style

Alammari, Saleh Ahmed, Abdullah Radhyan A. AlRuwaili, Abdulaziz Abdullah Almutairi, and Adeeb Naif Mhaileb Alshammari. "Treatment of resistant urinary tract infection: a systematic review." International Journal of Medicine in Developing Countries 5 (2021), 968-973. doi:10.24911/IJMDC.51-1612133177


MLA (The Modern Language Association) Style

Alammari, Saleh Ahmed, Abdullah Radhyan A. AlRuwaili, Abdulaziz Abdullah Almutairi, and Adeeb Naif Mhaileb Alshammari. "Treatment of resistant urinary tract infection: a systematic review." International Journal of Medicine in Developing Countries 5.3 (2021), 968-973. Print. doi:10.24911/IJMDC.51-1612133177


APA (American Psychological Association) Style

Alammari, S. A., AlRuwaili, . A. R. A., Almutairi, . A. A. & Alshammari, . A. N. M. (2021) Treatment of resistant urinary tract infection: a systematic review. International Journal of Medicine in Developing Countries, 5 (3), 968-973. doi:10.24911/IJMDC.51-1612133177


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