Abstract
Background: Drug addiction is considered a multi-factorial health problem that increases the risks of relapsing chronic disease. A multidisciplinary approach could be used to prevent and treat people who are drug addicts. Therefore, the current review aims to investigate the principles of drug addiction treatment.
Methods: Scientific articles that were related to the present topic were obtained using an online search process. The search process included various scientific websites such as Google Scholar and PubMed. We obtained 20 articles that matched with the current subject and were written in English. Of those 20 articles, four were excluded as they were published before 2000, or did not focus on the present topic, or were written in a language other than English; therefore, only 16 papers were included.
Results: Articles were selected depending on the inclusion criteria and the discussion of the subject is performed under the subheadings.
Conclusion: Drug addiction is a growing health problem that adversely affects personal life and the whole community. It had a harmful impact on the brain. Effective treatment programs, prevention strategies, or techniques, and modalities should be incorporated depending on research-based principles. Therefore, a set of treatment principles have been developed to prevent drug addiction among youth and adolescents and supporting/ encouraging the people who are addicted to drugs to access treatments. Cooperation between drug addiction treatment services and society and families is essential to remove any barriers restricting people to seek treatments.

Key words: A relapsing brain disease drug addiction, drug use disorders, drug abuse, HIV transmission.