Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection

Chittibabu Vatte; Hisham Abdulrahim Alkhalifah; Abdulaziz Waleed Almulhim; Riyadh Ahmed Alghamdi; Talal Aedh Albaqami; Othman Fahd Almuhanna; Faisal Maher Alfalah

doi:10.24911/IJMDC.51-1638900013

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Original Article
Online Published: 05 Jan 2022

IJMDC. 2022; 6(2): 310-315

doi: 10.24911/IJMDC.51-1638900013

Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection

Chittibabu Vatte, Hisham Abdulrahim Alkhalifah, Abdulaziz Waleed Almulhim, Riyadh Ahmed Alghamdi, Talal Aedh Albaqami, Othman Fahd Almuhanna, Faisal Maher Alfalah.

Abstract
Background: Coronavirus disease 2019 (COVID-19) has been a major source of health-related morbidity and mortality worldwide. Several recent reports emerged from evaluating large cohorts of patients infected with SARS-CoV-2 have shown that a small number of COVID-19 positive patients had a severe disease course. Reports have indicated that COVID-19 positive patients with cardiovascular disease are at a higher risk of developing severe phenotypes following hospitalization. Sickle cell disease (SCD) is very common in the Eastern Province of Saudi Arabia, and cardiovascular complications and acute chest syndrome are commonly associated with SCD. The main objective of the present study was to evaluate the severity of COVID-19 infection in sickle cell anemia patients compared to a non-SCD COVID-19 cohort.
Methods: Demographic, clinical, biochemical, and follow-up data were collected for 20 sickle cell anemia patients infected with COVID-19 and 50 normal COVID-19 patients at King Fahd Hospital of the University, Al Khobar.
Results: Analysis of the data showed that acute cardiovascular symptoms, acute respiratory distress syndrome, acute kidney syndrome, and shock were absent in the SCD patients compared to the normal COVID-19 cohort. The average temperature was lower, while the platelet count was higher in the SCD cohort than in non-SCD patients.
Conclusion: SCD patients infected with the COVID-19 virus showed a less severe course of COVID-19 than non- SCD patients with COVID-19.

Key words: COVID-19, sickle cell disease, cardiovascular, severity

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Pubmed Style

Vatte C, Alkhalifah HA, Almulhim AW, Alghamdi RA, Albaqami TA, Almuhanna OF, Alfalah FM. Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. IJMDC. 2022; 6(2): 310-315. doi:10.24911/IJMDC.51-1638900013

Web Style

Vatte C, Alkhalifah HA, Almulhim AW, Alghamdi RA, Albaqami TA, Almuhanna OF, Alfalah FM. Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. https://www.ijmdc.com/?mno=40241 [Access: October 14, 2025]. doi:10.24911/IJMDC.51-1638900013

AMA (American Medical Association) Style

Vatte C, Alkhalifah HA, Almulhim AW, Alghamdi RA, Albaqami TA, Almuhanna OF, Alfalah FM. Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. IJMDC. 2022; 6(2): 310-315. doi:10.24911/IJMDC.51-1638900013

Vancouver/ICMJE Style

Vatte C, Alkhalifah HA, Almulhim AW, Alghamdi RA, Albaqami TA, Almuhanna OF, Alfalah FM. Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. IJMDC. (2022), [cited October 14, 2025]; 6(2): 310-315. doi:10.24911/IJMDC.51-1638900013

Harvard Style

Vatte, C., Alkhalifah, . H. A., Almulhim, . A. W., Alghamdi, . R. A., Albaqami, . T. A., Almuhanna, . O. F. & Alfalah, . F. M. (2022) Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. IJMDC, 6 (2), 310-315. doi:10.24911/IJMDC.51-1638900013

Turabian Style

Vatte, Chittibabu, Hisham Abdulrahim Alkhalifah, Abdulaziz Waleed Almulhim, Riyadh Ahmed Alghamdi, Talal Aedh Albaqami, Othman Fahd Almuhanna, and Faisal Maher Alfalah. 2022. Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. International Journal of Medicine in Developing Countries, 6 (2), 310-315. doi:10.24911/IJMDC.51-1638900013

Chicago Style

Vatte, Chittibabu, Hisham Abdulrahim Alkhalifah, Abdulaziz Waleed Almulhim, Riyadh Ahmed Alghamdi, Talal Aedh Albaqami, Othman Fahd Almuhanna, and Faisal Maher Alfalah. "Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection." International Journal of Medicine in Developing Countries 6 (2022), 310-315. doi:10.24911/IJMDC.51-1638900013

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Vatte, C., Alkhalifah, . H. A., Almulhim, . A. W., Alghamdi, . R. A., Albaqami, . T. A., Almuhanna, . O. F. & Alfalah, . F. M. (2022) Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. International Journal of Medicine in Developing Countries, 6 (2), 310-315. doi:10.24911/IJMDC.51-1638900013

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