Original Article

IJMDC. 2022; 6(2): 310-315

Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection

Authors: Chittibabu Vatte, Hisham Abdulrahim Alkhalifah, Abdulaziz Waleed Almulhim, Riyadh Ahmed Alghamdi, Talal Aedh Albaqami, Othman Fahd Almuhanna, Faisal Maher Alfalah.

ABSTRACT

Background: Coronavirus disease 2019 (COVID-19) has been a major source of health-related morbidity and mortality worldwide. Several recent reports emerged from evaluating large cohorts of patients infected with SARS-CoV-2 have shown that a small number of COVID-19 positive patients had a severe disease course. Reports have indicated that COVID-19 positive patients with cardiovascular disease are at a higher risk of developing severe phenotypes following hospitalization. Sickle cell disease (SCD) is very common in the Eastern Province of Saudi Arabia, and cardiovascular complications and acute chest syndrome are commonly associated with SCD. The main objective of the present study was to evaluate the severity of COVID-19 infection in sickle cell anemia patients compared to a non-SCD COVID-19 cohort. Methods: Demographic, clinical, biochemical, and follow-up data were collected for 20 sickle cell anemia patients infected with COVID-19 and 50 normal COVID-19 patients at King Fahd Hospital of the University, Al Khobar. Results: Analysis of the data showed that acute cardiovascular symptoms, acute respiratory distress syndrome, acute kidney syndrome, and shock were absent in the SCD patients compared to the normal COVID-19 cohort. The average temperature was lower, while the platelet count was higher in the SCD cohort than in non-SCD patients. Conclusion: SCD patients infected with the COVID-19 virus showed a less severe course of COVID-19 than non- SCD patients with COVID-19.

Keywords:
COVID-19, sickle cell disease, cardiovascular, severity


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Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection


Authors
Chittibabu Vatte
Department of Biochemistry, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
PubMed articlesGoogle scholar articles

Hisham Abdulrahim Alkhalifah
Medical Intern, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
PubMed articlesGoogle scholar articles

Abdulaziz Waleed Almulhim
Medical Intern, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
PubMed articlesGoogle scholar articles

Riyadh Ahmed Alghamdi
Medical Intern, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
PubMed articlesGoogle scholar articles

Talal Aedh Albaqami
Medical Intern, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
PubMed articlesGoogle scholar articles

Othman Fahd Almuhanna
Medical Intern, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia
PubMed articlesGoogle scholar articles

Faisal Maher Alfalah
Medical Student, College of Medicine, King Faisal University, Al-Hofuf, Saudi Arabia
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Correspondence to:
. Hisham Abdulrahim Alkhalifah, Medical Intern, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.; hesham.a.alk@gmail.com

Publication history
Received 09 Dec 2021
Accepted 22 Dec 2021
Published online 01 Jan 2022
Published in print 19 Jan 2022

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Pubmed Style

Vatte C, Alkhalifah HA, Almulhim AW, Alghamdi RA, Albaqami TA, Almuhanna OF, Alfalah FM. Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. IJMDC. 2022; 6(2): 310-315. doi:10.24911/IJMDC.51-1638900013


Web Style

Vatte C, Alkhalifah HA, Almulhim AW, Alghamdi RA, Albaqami TA, Almuhanna OF, Alfalah FM. Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. https://www.ijmdc.com/?mno=40241 [Access: May 25, 2022]. doi:10.24911/IJMDC.51-1638900013


AMA (American Medical Association) Style

Vatte C, Alkhalifah HA, Almulhim AW, Alghamdi RA, Albaqami TA, Almuhanna OF, Alfalah FM. Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. IJMDC. 2022; 6(2): 310-315. doi:10.24911/IJMDC.51-1638900013


Vancouver/ICMJE Style

Vatte C, Alkhalifah HA, Almulhim AW, Alghamdi RA, Albaqami TA, Almuhanna OF, Alfalah FM. Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. IJMDC. (2022), [cited May 25, 2022]; 6(2): 310-315. doi:10.24911/IJMDC.51-1638900013


Harvard Style

Vatte, C., Alkhalifah, . H. A., Almulhim, . A. W., Alghamdi, . R. A., Albaqami, . T. A., Almuhanna, . O. F. & Alfalah, . F. M. (2022) Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. IJMDC, 6 (2), 310-315. doi:10.24911/IJMDC.51-1638900013


Turabian Style

Vatte, Chittibabu, Hisham Abdulrahim Alkhalifah, Abdulaziz Waleed Almulhim, Riyadh Ahmed Alghamdi, Talal Aedh Albaqami, Othman Fahd Almuhanna, and Faisal Maher Alfalah. 2022. Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. International Journal of Medicine in Developing Countries, 6 (2), 310-315. doi:10.24911/IJMDC.51-1638900013


Chicago Style

Vatte, Chittibabu, Hisham Abdulrahim Alkhalifah, Abdulaziz Waleed Almulhim, Riyadh Ahmed Alghamdi, Talal Aedh Albaqami, Othman Fahd Almuhanna, and Faisal Maher Alfalah. "Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection." International Journal of Medicine in Developing Countries 6 (2022), 310-315. doi:10.24911/IJMDC.51-1638900013


MLA (The Modern Language Association) Style

Vatte, Chittibabu, Hisham Abdulrahim Alkhalifah, Abdulaziz Waleed Almulhim, Riyadh Ahmed Alghamdi, Talal Aedh Albaqami, Othman Fahd Almuhanna, and Faisal Maher Alfalah. "Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection." International Journal of Medicine in Developing Countries 6.2 (2022), 310-315. Print. doi:10.24911/IJMDC.51-1638900013


APA (American Psychological Association) Style

Vatte, C., Alkhalifah, . H. A., Almulhim, . A. W., Alghamdi, . R. A., Albaqami, . T. A., Almuhanna, . O. F. & Alfalah, . F. M. (2022) Cardiac and other systemic complications in sickle cell anemia patients with COVID 19 infection. International Journal of Medicine in Developing Countries, 6 (2), 310-315. doi:10.24911/IJMDC.51-1638900013


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