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Original Article
Online Published: 20 Oct 2026
 


Therapeutic landscape of uterine fibroids management: a descriptive analysis of clinical trials registered on ClinicalTrials.gov

Inam S Alhabib, Sarah Saleh Alzahrani, Shahad Mohammed Albalawi, Taif Adel Salem Alharbi, Shahad Abdulrahman Alharthi, Taif Ibrahim Aseri, Remas Hamed Almohammdi, Waad Mohammed Alshamrani.


Abstract
Objective:
This study aimed to describe clinical trials for treatments of uterine fibroids registered at ClinicalTrials.gov.
Methods:
Descriptive analysis of ClinicalTrials.gov data obtained using the platform’s Application Programming Interface (API). Interventional and observational studies concerning uterine fibroids were included. The variables extracted were study design, recruitment status, geographic distribution, study phase, intervention category, and sponsor type.
Results:
Total 511 clinical trials were included in the analysis. The majority of studies were completed and interventional. Pharmacological therapies were the most studied intervention category, followed by surgical and minimally invasive treatment approaches. Most of the trials were conducted in North America and Europe. A substantial proportion of the research activity was industry-sponsored studies. Although there were many registered studies, only a few reported results publicly.
Conclusion:
The volume of clinical research on uterine fibroids has increased substantially, with an increasing focus on medical and less invasive treatment strategies. However, there are still major challenges such as poor reporting of results and geographic imbalance in research output. Increased transparency and worldwide engagement could improve the evidence base and future care of uterine fibroids.

Key words: Therapeutic landscape, uterine fibroids, management, clinical trials, ClinicalTrials.gov


 
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How to Cite this Article
Pubmed Style

Alhabib IS, Alzahrani SS, Albalawi SM, Alharbi TAS, Alharthi SA, Aseri TI, Almohammdi RH, Alshamrani WM. Therapeutic landscape of uterine fibroids management: a descriptive analysis of clinical trials registered on ClinicalTrials.gov. IJMDC. Online First: 20 Oct, 2026. doi:10.24911/IJMDC.51-1785297645

Web Style

Alhabib IS, Alzahrani SS, Albalawi SM, Alharbi TAS, Alharthi SA, Aseri TI, Almohammdi RH, Alshamrani WM. Therapeutic landscape of uterine fibroids management: a descriptive analysis of clinical trials registered on ClinicalTrials.gov. https://www.ijmdc.com/?mno=329352 [Access: October 20, 2026]. doi:10.24911/IJMDC.51-1785297645

AMA (American Medical Association) Style

Alhabib IS, Alzahrani SS, Albalawi SM, Alharbi TAS, Alharthi SA, Aseri TI, Almohammdi RH, Alshamrani WM. Therapeutic landscape of uterine fibroids management: a descriptive analysis of clinical trials registered on ClinicalTrials.gov. IJMDC. Online First: 20 Oct, 2026. doi:10.24911/IJMDC.51-1785297645


Vancouver/ICMJE Style

Alhabib IS, Alzahrani SS, Albalawi SM, Alharbi TAS, Alharthi SA, Aseri TI, Almohammdi RH, Alshamrani WM. Therapeutic landscape of uterine fibroids management: a descriptive analysis of clinical trials registered on ClinicalTrials.gov. IJMDC, [cited October 20, 2026]; Online First: 20 Oct, 2026. doi:10.24911/IJMDC.51-1785297645


Harvard Style

Alhabib, I. S., Alzahrani, . S. S., Albalawi, . S. M., Alharbi, . T. A. S., Alharthi, . S. A., Aseri, . T. I., Almohammdi, . R. H. & Alshamrani, . W. M. (2026) Therapeutic landscape of uterine fibroids management: a descriptive analysis of clinical trials registered on ClinicalTrials.gov. IJMDC, Online First: 20 Oct, 2026. doi:10.24911/IJMDC.51-1785297645


Turabian Style

Alhabib, Inam S, Sarah Saleh Alzahrani, Shahad Mohammed Albalawi, Taif Adel Salem Alharbi, Shahad Abdulrahman Alharthi, Taif Ibrahim Aseri, Remas Hamed Almohammdi, and Waad Mohammed Alshamrani. 2026. Therapeutic landscape of uterine fibroids management: a descriptive analysis of clinical trials registered on ClinicalTrials.gov. International Journal of Medicine in Developing Countries, Online First: 20 Oct, 2026. doi:10.24911/IJMDC.51-1785297645


Chicago Style

Alhabib, Inam S, Sarah Saleh Alzahrani, Shahad Mohammed Albalawi, Taif Adel Salem Alharbi, Shahad Abdulrahman Alharthi, Taif Ibrahim Aseri, Remas Hamed Almohammdi, and Waad Mohammed Alshamrani. "Therapeutic landscape of uterine fibroids management: a descriptive analysis of clinical trials registered on ClinicalTrials.gov." International Journal of Medicine in Developing Countries Online First: 20 Oct, 2026. doi:10.24911/IJMDC.51-1785297645


MLA (The Modern Language Association) Style

Alhabib, Inam S, Sarah Saleh Alzahrani, Shahad Mohammed Albalawi, Taif Adel Salem Alharbi, Shahad Abdulrahman Alharthi, Taif Ibrahim Aseri, Remas Hamed Almohammdi, and Waad Mohammed Alshamrani. "Therapeutic landscape of uterine fibroids management: a descriptive analysis of clinical trials registered on ClinicalTrials.gov." International Journal of Medicine in Developing Countries Online First: 20 Oct, 2026. Web. 20 Oct 2026 doi:10.24911/IJMDC.51-1785297645


APA (American Psychological Association) Style

Alhabib, I. S., Alzahrani, . S. S., Albalawi, . S. M., Alharbi, . T. A. S., Alharthi, . S. A., Aseri, . T. I., Almohammdi, . R. H. & Alshamrani, . W. M. (2026) Therapeutic landscape of uterine fibroids management: a descriptive analysis of clinical trials registered on ClinicalTrials.gov. International Journal of Medicine in Developing Countries, Online First: 20 Oct, 2026. doi:10.24911/IJMDC.51-1785297645




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