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2026, Vol: 10, Issue: 6
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Case Report
Online Published: 25 Apr 2026
 


Cutaneous leishmaniasis treated with itraconazole: a case report and review of literature

Jana Alharbi, Abdulaziz Alotaibi, Maria Alsulami, Mayar Alahmadi, Ghala Alotaibi, Fawaz Aljehani.


Abstract
Background: Cutaneous leishmaniasis (CL) is a parasitic infection caused by Leishmania species and is endemic in several regions, including Saudi Arabia.
Case Presentation: A case of a 61-year-old male was reported, who presented with a 2-month history of progressive, pruritic, erythematous, crusted facial plaques involving the nasal bridge and bilateral cheeks following travel to an endemic area. Histopathological examination demonstrated chronic granulomatous inflammation with intracellular amastigotes consistent with CL. The patient was treated with oral itraconazole (200 mg twice daily for 30 days), resulting in significant clinical improvement.
Conclusion: Oral itraconazole has been proven to be effective in managing CL; however, further research and clinical data are necessary to refine treatment protocols and assess the comparative effectiveness across different Leishmania species. Clinical suspicion and early detection are critical, and should involve a comprehensive approach, including clinical evaluation, histopathology, and laboratory testing.

Key words: Cutaneous leishmaniasis, treatment, itraconazole, Leishmania, case report, literature review, Saudi Arabia


 
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How to Cite this Article
Pubmed Style

Alharbi J, Alotaibi A, Alsulami M, Alahmadi M, Alotaibi G, Aljehani F. Cutaneous leishmaniasis treated with itraconazole: a case report and review of literature. IJMDC. 2026; 10(5): 1493-1496. doi:10.24911/IJMDC.51-1772052919

Web Style

Alharbi J, Alotaibi A, Alsulami M, Alahmadi M, Alotaibi G, Aljehani F. Cutaneous leishmaniasis treated with itraconazole: a case report and review of literature. https://www.ijmdc.com/?mno=311903 [Access: May 07, 2026]. doi:10.24911/IJMDC.51-1772052919

AMA (American Medical Association) Style

Alharbi J, Alotaibi A, Alsulami M, Alahmadi M, Alotaibi G, Aljehani F. Cutaneous leishmaniasis treated with itraconazole: a case report and review of literature. IJMDC. 2026; 10(5): 1493-1496. doi:10.24911/IJMDC.51-1772052919


Vancouver/ICMJE Style

Alharbi J, Alotaibi A, Alsulami M, Alahmadi M, Alotaibi G, Aljehani F. Cutaneous leishmaniasis treated with itraconazole: a case report and review of literature. IJMDC. (2026), [cited May 07, 2026]; 10(5): 1493-1496. doi:10.24911/IJMDC.51-1772052919


Harvard Style

Alharbi, J., Alotaibi, . A., Alsulami, . M., Alahmadi, . M., Alotaibi, . G. & Aljehani, . F. (2026) Cutaneous leishmaniasis treated with itraconazole: a case report and review of literature. IJMDC, 10 (5), 1493-1496. doi:10.24911/IJMDC.51-1772052919


Turabian Style

Alharbi, Jana, Abdulaziz Alotaibi, Maria Alsulami, Mayar Alahmadi, Ghala Alotaibi, and Fawaz Aljehani. 2026. Cutaneous leishmaniasis treated with itraconazole: a case report and review of literature. International Journal of Medicine in Developing Countries, 10 (5), 1493-1496. doi:10.24911/IJMDC.51-1772052919


Chicago Style

Alharbi, Jana, Abdulaziz Alotaibi, Maria Alsulami, Mayar Alahmadi, Ghala Alotaibi, and Fawaz Aljehani. "Cutaneous leishmaniasis treated with itraconazole: a case report and review of literature." International Journal of Medicine in Developing Countries 10 (2026), 1493-1496. doi:10.24911/IJMDC.51-1772052919


MLA (The Modern Language Association) Style

Alharbi, Jana, Abdulaziz Alotaibi, Maria Alsulami, Mayar Alahmadi, Ghala Alotaibi, and Fawaz Aljehani. "Cutaneous leishmaniasis treated with itraconazole: a case report and review of literature." International Journal of Medicine in Developing Countries 10.5 (2026), 1493-1496. Print. doi:10.24911/IJMDC.51-1772052919


APA (American Psychological Association) Style

Alharbi, J., Alotaibi, . A., Alsulami, . M., Alahmadi, . M., Alotaibi, . G. & Aljehani, . F. (2026) Cutaneous leishmaniasis treated with itraconazole: a case report and review of literature. International Journal of Medicine in Developing Countries, 10 (5), 1493-1496. doi:10.24911/IJMDC.51-1772052919




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