E-ISSN 1658-7820
 
2026, Vol: 10, Issue: 6
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Case Report
Online Published: 25 Mar 2026
 


Pemphigus vulgaris mimicking Behçet disease: a case report

Rawan Mahmoud Alanazi, Mohammad Kaled Almazied, Sharifah Hussain Almasoud, Deema Tawfiq Almodihem, Haneen Nasser Abanmi, Abdulkareem Ibrahim Alfuraih.


Abstract
A 58-year-old female, known case of diabetes mellitus, followed up with rheumatology as a case of Behçet disease, developed sudden-onset generalized flaccid bullae and mucosal erosions shortly after switching from azathioprine to adalimumab. Histopathology and direct immunofluorescence were consistent with pemphigus vulgaris. She was successfully treated with systemic corticosteroids, azathioprine, and rituximab, showing excellent clinical improvement. The patient was seen in the clinic after 2 months with no relapse. This case highlights the importance of recognizing overlapping autoimmune phenomena in Behçet disease and differentiating true Behçet mucocutaneous activity from drug-induced or coincident autoimmune blistering disorders.

Key words: Keywords: Pemphigus vulgaris, Behçet disease, Autoimmune blistering disease, Adalimumab, TNF-α inhibitor, Rituximab


 
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How to Cite this Article
Pubmed Style

Alanazi RM, Almazied MK, Almasoud SH, Almodihem DT, Abanmi HN, Alfuraih AI. Pemphigus vulgaris mimicking Behçet disease: a case report. IJMDC. 2026; 10(4): 1282-1284. doi:10.24911/IJMDC.51-1770890873

Web Style

Alanazi RM, Almazied MK, Almasoud SH, Almodihem DT, Abanmi HN, Alfuraih AI. Pemphigus vulgaris mimicking Behçet disease: a case report. https://www.ijmdc.com/?mno=310254 [Access: April 07, 2026]. doi:10.24911/IJMDC.51-1770890873

AMA (American Medical Association) Style

Alanazi RM, Almazied MK, Almasoud SH, Almodihem DT, Abanmi HN, Alfuraih AI. Pemphigus vulgaris mimicking Behçet disease: a case report. IJMDC. 2026; 10(4): 1282-1284. doi:10.24911/IJMDC.51-1770890873


Vancouver/ICMJE Style

Alanazi RM, Almazied MK, Almasoud SH, Almodihem DT, Abanmi HN, Alfuraih AI. Pemphigus vulgaris mimicking Behçet disease: a case report. IJMDC. (2026), [cited April 07, 2026]; 10(4): 1282-1284. doi:10.24911/IJMDC.51-1770890873


Harvard Style

Alanazi, R. M., Almazied, . M. K., Almasoud, . S. H., Almodihem, . D. T., Abanmi, . H. N. & Alfuraih, . A. I. (2026) Pemphigus vulgaris mimicking Behçet disease: a case report. IJMDC, 10 (4), 1282-1284. doi:10.24911/IJMDC.51-1770890873


Turabian Style

Alanazi, Rawan Mahmoud, Mohammad Kaled Almazied, Sharifah Hussain Almasoud, Deema Tawfiq Almodihem, Haneen Nasser Abanmi, and Abdulkareem Ibrahim Alfuraih. 2026. Pemphigus vulgaris mimicking Behçet disease: a case report. International Journal of Medicine in Developing Countries, 10 (4), 1282-1284. doi:10.24911/IJMDC.51-1770890873


Chicago Style

Alanazi, Rawan Mahmoud, Mohammad Kaled Almazied, Sharifah Hussain Almasoud, Deema Tawfiq Almodihem, Haneen Nasser Abanmi, and Abdulkareem Ibrahim Alfuraih. "Pemphigus vulgaris mimicking Behçet disease: a case report." International Journal of Medicine in Developing Countries 10 (2026), 1282-1284. doi:10.24911/IJMDC.51-1770890873


MLA (The Modern Language Association) Style

Alanazi, Rawan Mahmoud, Mohammad Kaled Almazied, Sharifah Hussain Almasoud, Deema Tawfiq Almodihem, Haneen Nasser Abanmi, and Abdulkareem Ibrahim Alfuraih. "Pemphigus vulgaris mimicking Behçet disease: a case report." International Journal of Medicine in Developing Countries 10.4 (2026), 1282-1284. Print. doi:10.24911/IJMDC.51-1770890873


APA (American Psychological Association) Style

Alanazi, R. M., Almazied, . M. K., Almasoud, . S. H., Almodihem, . D. T., Abanmi, . H. N. & Alfuraih, . A. I. (2026) Pemphigus vulgaris mimicking Behçet disease: a case report. International Journal of Medicine in Developing Countries, 10 (4), 1282-1284. doi:10.24911/IJMDC.51-1770890873




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