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Review Article

Online Publishing Date:
31 / 12 / 2020

 


Risk factors of post-ureteroscopy sepsis: a systematic review and meta-analysis

Abdullah Falah Alanazi, Saleh Alshami Alruwaili, Saud Omar Zakaria, Yousef Mukhlef Alanazi, Ali Tareq Almoumen.


Abstract
With the expansion of Ureteroscopy (URS), infectious complications have become problems that can't be ignored, and sometimes lethal morbidities can occur. The present study aims to determine the risk factors of infectious complications (sepsis) post-URS patients. A systematic search was performed over different medical databases to identify Urology studies, which studied the outcome of the Sepsis URS group versus the Control URS group of post-ureteroscopy patients. Using the meta-analysis process, either with fixed or random-effects models, we conducted a meta-analysis on risk factors (gender, diabetes mellitus, and stent insertion) as primary main outcomes. Six studies were identified involving 3660 patients, 169 in the Sepsis URS group, and 3491 in the Control URS group. The meta-analysis process revealed that the overall pooled prevalence of sepsis in URS patients = 6.3 %. We found a highly significant increase in sepsis in female URS patients and a significant increase in prior stent insertion, compared to the Control URS group (p < 0.001, p = 0.034 respectively). But we found a non-significant difference in Diabetes Mellitus (DM) prevalence in the Sepsis URS group compared to the Control URS group (p > 0.05). To conclude, patients who undergo ureteroscopy after ureteric stent insertion have a higher risk of postoperative sepsis. Prolonged stent dwelling time, sepsis as an indication for stent insertion, and female gender are independent risk factors. Stent placement should be considered cautiously, and if inserted, ureteroscopy should be performed within 1 month.

Key words: Sepsis, infection, post-ureteroscopy


 
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How to Cite this Article
Pubmed Style

Alanazi AF, Alruwaili SA, Zakaria SO, Alanazi YM, Almoumen AT. Risk factors of post-ureteroscopy sepsis: a systematic review and meta-analysis. IJMDC. Online First: 31 Dec, 2020. doi:10.24911/IJMDC.51-1607940935

Web Style

Alanazi AF, Alruwaili SA, Zakaria SO, Alanazi YM, Almoumen AT. Risk factors of post-ureteroscopy sepsis: a systematic review and meta-analysis. https://www.ijmdc.com/?mno=30295 [Access: March 26, 2024]. doi:10.24911/IJMDC.51-1607940935

AMA (American Medical Association) Style

Alanazi AF, Alruwaili SA, Zakaria SO, Alanazi YM, Almoumen AT. Risk factors of post-ureteroscopy sepsis: a systematic review and meta-analysis. IJMDC. Online First: 31 Dec, 2020. doi:10.24911/IJMDC.51-1607940935


Vancouver/ICMJE Style

Alanazi AF, Alruwaili SA, Zakaria SO, Alanazi YM, Almoumen AT. Risk factors of post-ureteroscopy sepsis: a systematic review and meta-analysis. IJMDC, [cited March 26, 2024]; Online First: 31 Dec, 2020. doi:10.24911/IJMDC.51-1607940935


Harvard Style

Alanazi, A. F., Alruwaili, . S. A., Zakaria, . S. O., Alanazi, . Y. M. & Almoumen, . A. T. (2021) Risk factors of post-ureteroscopy sepsis: a systematic review and meta-analysis. IJMDC, Online First: 31 Dec, 2020. doi:10.24911/IJMDC.51-1607940935


Turabian Style

Alanazi, Abdullah Falah, Saleh Alshami Alruwaili, Saud Omar Zakaria, Yousef Mukhlef Alanazi, and Ali Tareq Almoumen. 2021. Risk factors of post-ureteroscopy sepsis: a systematic review and meta-analysis. International Journal of Medicine in Developing Countries, Online First: 31 Dec, 2020. doi:10.24911/IJMDC.51-1607940935


Chicago Style

Alanazi, Abdullah Falah, Saleh Alshami Alruwaili, Saud Omar Zakaria, Yousef Mukhlef Alanazi, and Ali Tareq Almoumen. "Risk factors of post-ureteroscopy sepsis: a systematic review and meta-analysis." International Journal of Medicine in Developing Countries Online First: 31 Dec, 2020. doi:10.24911/IJMDC.51-1607940935


MLA (The Modern Language Association) Style

Alanazi, Abdullah Falah, Saleh Alshami Alruwaili, Saud Omar Zakaria, Yousef Mukhlef Alanazi, and Ali Tareq Almoumen. "Risk factors of post-ureteroscopy sepsis: a systematic review and meta-analysis." International Journal of Medicine in Developing Countries Online First: 31 Dec, 2020. Web. 26 Mar 2024 doi:10.24911/IJMDC.51-1607940935


APA (American Psychological Association) Style

Alanazi, A. F., Alruwaili, . S. A., Zakaria, . S. O., Alanazi, . Y. M. & Almoumen, . A. T. (2021) Risk factors of post-ureteroscopy sepsis: a systematic review and meta-analysis. International Journal of Medicine in Developing Countries, Online First: 31 Dec, 2020. doi:10.24911/IJMDC.51-1607940935




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