E-ISSN 1658-7820
 
2025, Vol: 9, Issue: 8
9 / 8Current Issue Online First Archive Aims and Scope Abstracting & Indexing Most Accessed Articles Most Downloaded Articles Most Cited Articles

Original Article
Online Published: 10 Oct 2024
 


Impact of consanguinity on epilepsy risk in Al-Jouf, Saudi Arabia: a hospital-based cross-sectional study

Mubarak Alruwaili, Raed Alruwaili, Aseel Awad Alsaidan, Monay Bassam Alkhaldi Alkhaldi, Hana Nasser Alkhalifah, Rahaf Marshad Alnasser, Amirah Mojidea Alshammari, Reem Maqbul Alruwaili, Rehana Basri.


Abstract
Background: Epilepsy is a widespread neurological condition with significant social and psychological consequences. In regions like Al-Jouf, Saudi Arabia, where consanguineous marriages are prevalent, understanding the genetic factors contributing to epilepsy, including the role of consanguinity, is of great interest. This study aims to explore the types of epilepsy, associated risk factors, and the influence of consanguinity among patients Al-Jouf.
Methods: A hospital-based cross-sectional study was conducted at Prince Mutaib Bin Abdulaziz Hospital, Sakaka, Al-Jouf. The study included all patients diagnosed with epilepsy who attended the hospital’s neurology clinic or were admitted during the study period. Data were collected through structured interviews using a detailed questionnaire and analyzed using SPSS version 22. Statistical significance was determined at p < 0.05.
Results: Seventy-two patients participated, with a majority being male (61.1%) and most over the age of 18 (79.2%). Idiopathic epilepsy was the most common etiology (72.2%), followed by symptomatic causes (27.8%). Significant risk factors included a family history of epilepsy (23%), head trauma (17%), and febrile seizures (14%). The association between parental consanguinity and epilepsy was minimal, without any statistically significant relationship.
Conclusion: Family history of epilepsy and head trauma are important risk factors in this population, while consanguinity appears to play a lesser role. These findings suggest that public health initiatives should focus on nongenetic factors, such as preventing head injuries while managing epilepsy in this region. Further research is warranted to explore the complex genetic and environmental interactions contributing to epilepsy.

Key words: Epilepsy, Risk Factors, Consanguinity, Seizure Triggers, Saudi Arabia, Cross-Sectional Study


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Mubarak Alruwaili
Articles by Raed AlRuwaili
Articles by Aseel Awad Alsaidan
Articles by Monay Bassam Alkhaldi Alkhaldi
Articles by Hana Nasser Alkhalifah
Articles by Rahaf Marshad Alnasser
Articles by Amirah Mojidea AlShammari
Articles by Reem Maqbul Alruwaili
Articles by Rehana Basri
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Alruwaili M, Alruwaili R, Alsaidan AA, Alkhaldi MBA, Alkhalifah HN, Alnasser RM, Alshammari AM, Alruwaili RM, Basri R. Impact of consanguinity on epilepsy risk in Al-Jouf, Saudi Arabia: a hospital-based cross-sectional study. IJMDC. 2024; 8(9): 2279-2285. doi:10.24911/IJMDC.51-1725386808

Web Style

Alruwaili M, Alruwaili R, Alsaidan AA, Alkhaldi MBA, Alkhalifah HN, Alnasser RM, Alshammari AM, Alruwaili RM, Basri R. Impact of consanguinity on epilepsy risk in Al-Jouf, Saudi Arabia: a hospital-based cross-sectional study. https://www.ijmdc.com/?mno=218712 [Access: October 12, 2025]. doi:10.24911/IJMDC.51-1725386808

AMA (American Medical Association) Style

Alruwaili M, Alruwaili R, Alsaidan AA, Alkhaldi MBA, Alkhalifah HN, Alnasser RM, Alshammari AM, Alruwaili RM, Basri R. Impact of consanguinity on epilepsy risk in Al-Jouf, Saudi Arabia: a hospital-based cross-sectional study. IJMDC. 2024; 8(9): 2279-2285. doi:10.24911/IJMDC.51-1725386808


Vancouver/ICMJE Style

Alruwaili M, Alruwaili R, Alsaidan AA, Alkhaldi MBA, Alkhalifah HN, Alnasser RM, Alshammari AM, Alruwaili RM, Basri R. Impact of consanguinity on epilepsy risk in Al-Jouf, Saudi Arabia: a hospital-based cross-sectional study. IJMDC. (2024), [cited October 12, 2025]; 8(9): 2279-2285. doi:10.24911/IJMDC.51-1725386808


Harvard Style

Alruwaili, M., Alruwaili, . R., Alsaidan, . A. A., Alkhaldi, . M. B. A., Alkhalifah, . H. N., Alnasser, . R. M., Alshammari, . A. M., Alruwaili, . R. M. & Basri, . R. (2024) Impact of consanguinity on epilepsy risk in Al-Jouf, Saudi Arabia: a hospital-based cross-sectional study. IJMDC, 8 (9), 2279-2285. doi:10.24911/IJMDC.51-1725386808


Turabian Style

Alruwaili, Mubarak, Raed Alruwaili, Aseel Awad Alsaidan, Monay Bassam Alkhaldi Alkhaldi, Hana Nasser Alkhalifah, Rahaf Marshad Alnasser, Amirah Mojidea Alshammari, Reem Maqbul Alruwaili, and Rehana Basri. 2024. Impact of consanguinity on epilepsy risk in Al-Jouf, Saudi Arabia: a hospital-based cross-sectional study. International Journal of Medicine in Developing Countries, 8 (9), 2279-2285. doi:10.24911/IJMDC.51-1725386808


Chicago Style

Alruwaili, Mubarak, Raed Alruwaili, Aseel Awad Alsaidan, Monay Bassam Alkhaldi Alkhaldi, Hana Nasser Alkhalifah, Rahaf Marshad Alnasser, Amirah Mojidea Alshammari, Reem Maqbul Alruwaili, and Rehana Basri. "Impact of consanguinity on epilepsy risk in Al-Jouf, Saudi Arabia: a hospital-based cross-sectional study." International Journal of Medicine in Developing Countries 8 (2024), 2279-2285. doi:10.24911/IJMDC.51-1725386808


MLA (The Modern Language Association) Style

Alruwaili, Mubarak, Raed Alruwaili, Aseel Awad Alsaidan, Monay Bassam Alkhaldi Alkhaldi, Hana Nasser Alkhalifah, Rahaf Marshad Alnasser, Amirah Mojidea Alshammari, Reem Maqbul Alruwaili, and Rehana Basri. "Impact of consanguinity on epilepsy risk in Al-Jouf, Saudi Arabia: a hospital-based cross-sectional study." International Journal of Medicine in Developing Countries 8.9 (2024), 2279-2285. Print. doi:10.24911/IJMDC.51-1725386808


APA (American Psychological Association) Style

Alruwaili, M., Alruwaili, . R., Alsaidan, . A. A., Alkhaldi, . M. B. A., Alkhalifah, . H. N., Alnasser, . R. M., Alshammari, . A. M., Alruwaili, . R. M. & Basri, . R. (2024) Impact of consanguinity on epilepsy risk in Al-Jouf, Saudi Arabia: a hospital-based cross-sectional study. International Journal of Medicine in Developing Countries, 8 (9), 2279-2285. doi:10.24911/IJMDC.51-1725386808




Most Viewed Articles
Most Downloaded
Most Cited Articles

About International Journal of Medicine in Developing Countries

International Journal of Medicine in Developing Countries is a peer-reviewed, open access international medical journal. Journal Title Internat ... Read more.



For best results, please use Internet Explorer or Google Chrome.

Contact Information

Publisher: Discover STM Publishing Ltd. 164 Moyville. Rathfarnham, Dublin, D16Y4E, Ireland

Hours:  M-F: 7:30am - 4:30pm 

Fax: +353 (0)1 633 5037 

Emails:

Journal Editorial Office:  contact@ijmdc.com

All queries regarding the publishing or accepting of the manuscript should be directed to the Journal Editorial Office at Riyadh, Saudi Arabia. 

Publishing and Hosting service is provided by Discover STM (Ireland):  contact@discoverpublish.com
POLICIES & JOURNAL LINKS
Author Login
Reviewer Login
Author LoginReviewer LoginAbout PublisherEditorial PoliciesEditorial Review PolicyPeer Review PolicyEditorial & Peer Review ProcessAuthor's Rights and ObligationsPublication Ethics and Publication Malpractice StatementConflict of Interest PolicyPlagiarism PolicyProtection of Research Participants (Statement On Human And Animal Rights)Corrections, Retractions & Expressions of ConcernSelf-Archiving PoliciesAdvertising PolicyLicense InformationCopyright Information