E-ISSN 1658-7820
 

Original Article

Online Publishing Date:
03 / 05 / 2024

 


Prevalence of food allergy and other atopy among children with eosinophilic esophagitis in single center retrospective study, Riyadh, Saudi Arabia

Yasir Albarrak, Emadia Alaki, Wadha Aldosari, Musa Alkhormi, Ahmed Alawfi, Muhannad Almajed, Husam Islam, Ghannam Alghannam, Abdulwahab Alayoubi, Amani Siddig, Meshari Aladhadh, Abdulrahman Alamri.


Abstract
Background: Eosinophilic esophagitis (EoE) is increasingly recognized as a significant public health issue in pediatric populations. The multifaceted mechanisms involving genetic, environmental, and immunological factors, particularly the role of allergens, are central to understanding EoE’s pathogenesis. This study aims to analyze the prevalence of food allergies and atopic diseases among children diagnosed with EoE, offering insights into their interrelations and informing improved management strategies.
Methods: This retrospective study analyzed 47 pediatric patients diagnosed with EoE at the Allergy and Gastroenterology Clinic, Children’s Hospital, King Saud Medical City, Riyadh, from February 2012 to December 2018. Patients were selected based on documented food allergies, anaphylactic reactions, comorbid atopic conditions, positive radioallergosorbent test (RAST) results, and elevated eosinophilia. Data collection involved medical records and detailed family questionnaires. Immunological assays and endoscopic biopsies were used for diagnosis, with EoE defined as more than 15 eosinophils/high power field.
Results: The study population predominantly comprised Saudi males, with a mean age of 8.36 years. A significant portion had consanguineous parents. Notable findings include a high prevalence of asthma (46.8%), allergic rhinitis (23.4%), and eczema (25.5%). The most common food allergens identified were peanuts, nuts, and seafood. Asthma severity varied, with ventolin and fluticasone being the most prescribed medications. Laboratory investigations showed elevated white blood cell, absolute neutrophil count, lymph, eosinophil sedimentation rat (ESO), eosinophil percentage, and immunoglobulin E (IgE) levels. RAST indicated specific allergen sensitivities in 34.0% of patients.
Conclusion: This study provides essential insights into the demographic, clinical, and therapeutic aspects of pediatric EoE, emphasizing the importance of a comprehensive, personalized approach to management.

Key words: Eosinophilic esophagitis, pediatric allergy, food allergies, atopic diseases, Saudi Arabia


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Yasir Albarrak
Articles by Emadia Alaki
Articles by Wadha Aldosari
Articles by Musa Alkhormi
Articles by Ahmed Alawfi
Articles by Muhannad Almajed
Articles by Husam Islam
Articles by Ghannam Alghannam
Articles by Abdulwahab Alayoubi
Articles by Amani Siddig
Articles by Meshari Aladhadh
Articles by Abdulrahman Alamri
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Albarrak Y, Alaki E, Aldosari W, Alkhormi M, Alawfi A, Almajed M, Islam H, Alghannam G, Alayoubi A, Siddig A, Aladhadh M, Alamri A. Prevalence of food allergy and other atopy among children with eosinophilic esophagitis in single center retrospective study, Riyadh, Saudi Arabia. IJMDC. 2024; 8(6): 1445-1455. doi:10.24911/IJMDC.51-1713018581


Web Style

Albarrak Y, Alaki E, Aldosari W, Alkhormi M, Alawfi A, Almajed M, Islam H, Alghannam G, Alayoubi A, Siddig A, Aladhadh M, Alamri A. Prevalence of food allergy and other atopy among children with eosinophilic esophagitis in single center retrospective study, Riyadh, Saudi Arabia. https://www.ijmdc.com/?mno=197570 [Access: July 14, 2024]. doi:10.24911/IJMDC.51-1713018581


AMA (American Medical Association) Style

Albarrak Y, Alaki E, Aldosari W, Alkhormi M, Alawfi A, Almajed M, Islam H, Alghannam G, Alayoubi A, Siddig A, Aladhadh M, Alamri A. Prevalence of food allergy and other atopy among children with eosinophilic esophagitis in single center retrospective study, Riyadh, Saudi Arabia. IJMDC. 2024; 8(6): 1445-1455. doi:10.24911/IJMDC.51-1713018581



Vancouver/ICMJE Style

Albarrak Y, Alaki E, Aldosari W, Alkhormi M, Alawfi A, Almajed M, Islam H, Alghannam G, Alayoubi A, Siddig A, Aladhadh M, Alamri A. Prevalence of food allergy and other atopy among children with eosinophilic esophagitis in single center retrospective study, Riyadh, Saudi Arabia. IJMDC. (2024), [cited July 14, 2024]; 8(6): 1445-1455. doi:10.24911/IJMDC.51-1713018581



Harvard Style

Albarrak, Y., Alaki, . E., Aldosari, . W., Alkhormi, . M., Alawfi, . A., Almajed, . M., Islam, . H., Alghannam, . G., Alayoubi, . A., Siddig, . A., Aladhadh, . M. & Alamri, . A. (2024) Prevalence of food allergy and other atopy among children with eosinophilic esophagitis in single center retrospective study, Riyadh, Saudi Arabia. IJMDC, 8 (6), 1445-1455. doi:10.24911/IJMDC.51-1713018581



Turabian Style

Albarrak, Yasir, Emadia Alaki, Wadha Aldosari, Musa Alkhormi, Ahmed Alawfi, Muhannad Almajed, Husam Islam, Ghannam Alghannam, Abdulwahab Alayoubi, Amani Siddig, Meshari Aladhadh, and Abdulrahman Alamri. 2024. Prevalence of food allergy and other atopy among children with eosinophilic esophagitis in single center retrospective study, Riyadh, Saudi Arabia. International Journal of Medicine in Developing Countries, 8 (6), 1445-1455. doi:10.24911/IJMDC.51-1713018581



Chicago Style

Albarrak, Yasir, Emadia Alaki, Wadha Aldosari, Musa Alkhormi, Ahmed Alawfi, Muhannad Almajed, Husam Islam, Ghannam Alghannam, Abdulwahab Alayoubi, Amani Siddig, Meshari Aladhadh, and Abdulrahman Alamri. "Prevalence of food allergy and other atopy among children with eosinophilic esophagitis in single center retrospective study, Riyadh, Saudi Arabia." International Journal of Medicine in Developing Countries 8 (2024), 1445-1455. doi:10.24911/IJMDC.51-1713018581



MLA (The Modern Language Association) Style

Albarrak, Yasir, Emadia Alaki, Wadha Aldosari, Musa Alkhormi, Ahmed Alawfi, Muhannad Almajed, Husam Islam, Ghannam Alghannam, Abdulwahab Alayoubi, Amani Siddig, Meshari Aladhadh, and Abdulrahman Alamri. "Prevalence of food allergy and other atopy among children with eosinophilic esophagitis in single center retrospective study, Riyadh, Saudi Arabia." International Journal of Medicine in Developing Countries 8.6 (2024), 1445-1455. Print. doi:10.24911/IJMDC.51-1713018581



APA (American Psychological Association) Style

Albarrak, Y., Alaki, . E., Aldosari, . W., Alkhormi, . M., Alawfi, . A., Almajed, . M., Islam, . H., Alghannam, . G., Alayoubi, . A., Siddig, . A., Aladhadh, . M. & Alamri, . A. (2024) Prevalence of food allergy and other atopy among children with eosinophilic esophagitis in single center retrospective study, Riyadh, Saudi Arabia. International Journal of Medicine in Developing Countries, 8 (6), 1445-1455. doi:10.24911/IJMDC.51-1713018581





Most Viewed Articles
Most Accessed Articles

  • Marginal adaptation of fixed prosthodontics
    Shahad Mohammed Halawani, Sahar Amer Al-Harbi
    IJMDC. 2017; 1(2): 78-84
    » Abstract » doi: 10.24911/IJMDC.1.2.7

  • Parasites in central nervous system
    Amal Ahmed Mohamed, Asmaa Mohamed Mansour
    IJMDC. 2017; 1(2): 72-77
    » Abstract » doi: 10.24911/IJMDC.1.2.6

  • Non-diabetic retinopathy: a case report
    Hassan F. Alkwikbi, Nabil Mamon Abdelfattah, Haithem Mamon Abdelfattah
    IJMDC. 2017; 1(1): 33-37
    » Abstract » doi: 10.24911/IJMDC.1.1.6

  • Vitamin D deficiency among high school female students in Riyadh
    Sahar Mohsen Aldhafeeri, Fatemah Ibraheem Alrawaji, Abrar Mubarak Algharbi, Alanoud Abdullah Alhessan, Ayat Sami Qabaja, Ghaleah Abdulaziz Alnassar, Ghaliah Ofayn Alsulami, Mashael Belal Alrubaian, Norah Abdulaziz Alhatim, Salehah Salih Alotaibi, Zahra Ali Alkhamees
    IJMDC. 2017; 1(1): 18-23
    » Abstract » doi: 10.24911/IJMDC.1.1.4

  • Prognosis of chronic complications of diabetes mellitus (DM) after multiple events of diabetic ketoacidosis (DKA)
    Baraa Faiez Rajab, Anwar Essa Alamrim, Ali Essa Alamri
    IJMDC. 2019; 3(5): 474-479
    » Abstract » doi: 10.24911/IJMDC.51-1546551993

  • Most Downloaded
    Top Downloaded Articles

  • Anti-IL-17 markedly inhibited the in vitro granuloma induced by Schistosoma mansoni soluble egg antigen.
    Asmaa Ezz, Irene S. Gmail, Fatma Elzahraa H. Salem, Rabab Salama, Soad Nady
    IJMDC. 2018; 2(January 2018): 38-46
    » Abstract » doi: 10.24911/IJMDC.2.1.7

  • Vitamin D deficiency among high school female students in Riyadh
    Sahar Mohsen Aldhafeeri, Fatemah Ibraheem Alrawaji, Abrar Mubarak Algharbi, Alanoud Abdullah Alhessan, Ayat Sami Qabaja, Ghaleah Abdulaziz Alnassar, Ghaliah Ofayn Alsulami, Mashael Belal Alrubaian, Norah Abdulaziz Alhatim, Salehah Salih Alotaibi, Zahra Ali Alkhamees
    IJMDC. 2017; 1(1): 18-23
    » Abstract » doi: 10.24911/IJMDC.1.1.4

  • Antibiotic Resistance Crisis
    Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
    IJMDC. 2019; 3(6): 561-564
    » Abstract » doi: 10.24911/IJMDC.51-1549060699

  • The knowledge of mothers about children malnutrition and associated factors
    Anas Abdulrahman Aljohani, Mujahid Abdulrahman Aljohani
    IJMDC. 2020; 4(1): 7-11
    » Abstract » doi: 10.24911/IJMDC.51-1541620358

  • Knowledge and attitude of caregivers of cerebral palsy children in Riyadh city
    Abdulaziz Alruwaished, Baleegh Ali, Lubna Abdullah Alhowaimil , Abaraa adullah Alhowaimil, Najd Abdullah Alhowaimil, Aminah Alessa
    IJMDC. 2020; 4(1): 12-17
    » Abstract » doi: 10.24911/IJMDC.51-1547833051

  • Most Cited Articles
    Most Cited Articles

  • Antibiotic Resistance Crisis
    Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
    IJMDC. 2019; 3(6): 561-564
    » Abstract » doi: 10.24911/IJMDC.51-1549060699
    Cited : 34 times [Click to see citing articles]

  • Prevalence of depression, anxiety and stress among diabetes mellitus patients in Arar, Northern Saudi Arabia
    AMohammed Elamin Mukrim, Nujud Muteb D. Alshammari, Wurud Muteb D. Alshammari, Maali Subhi T. Alshammari, Yousef Nasif R. Alshammari, Abdulaziz Sael M. Alshammari, Maisa Hamad F. Alanazi, Abdulelah Abdulrhman F. Alzammam, Muharib Mana M. Alshammari, Slwa Khaled Abu Asyah, Aseel Jamal Alzuhayri, Mushref Saeid Alshammari
    IJMDC. 2019; 3(3): 229-233
    » Abstract » doi: 10.24911/IJMDC.51-1542576396
    Cited : 8 times [Click to see citing articles]

  • Knowledge, attitude, and practice of breast self-examination toward breast cancer among female students at King Saud University in Riyadh, Saudi Arabia
    Abdullah Nasser Alomair, Dania Ghazi Felemban, Mohannad Sami Felemban, Jameel Abdullah Awadain, Ammar Saud Altowairqi, Nawaf Fawzan Alfawzan, Fatimah Mohammed Almazayen, Abdulrahman Jalwi Korkoman, Nawaf Saad Alrusayyis
    IJMDC. 2020; 4(2): 429-434
    » Abstract » doi: 10.24911/IJMDC.51-1576668182
    Cited : 8 times [Click to see citing articles]

  • Population awareness about rheumatoid arthritis in Jazan region, Saudi Arabia
    Ahmad Ali Hazzazi, Mohssen Hassen Ageeli, Ahmed Ali Muyidi, Abdulaziz Mohammad Abulgasim, Abdullah Ahmad Yateemi, Nabil Alhakami
    IJMDC. 2020; 4(3): 668-675
    » Abstract » doi: 10.24911/IJMDC.51-1576010943
    Cited : 4 times [Click to see citing articles]

  • Prevalence and factors associated with depression among health care workers in National Guard Hospital in Riyadh, KSA
    Noor Mohammad AlFahhad
    IJMDC. 2018; 2(September 2018): 92-96
    » Abstract » doi: 10.24911/IJMDC.51-1526306040
    Cited : 4 times [Click to see citing articles]