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Original Article
Online Published: 03 May 2024
 


Prevalence of self-prescribed Vitamin A analogs and awareness of related adverse effects

Maram S. Alruwaili, Mohammed A. Alahmadi, Rabab H. Alzanadi, Tharaa N. Almughera, Danyah S. Almohsen, Sarah A. Bukhamsin, Kholoud M. Alghamdi, Renad M. Alhaqbani, Sahar S. Alsifri, Reemah F. Alqahtani, Haifa A. Alfalah, Moteb K. Alotaibi.


Abstract
Background: Topical Vitamin A analogs (Retinoids) are approved treatments for acne vulgaris impacting the quality of life. Self-prescription of retinoids is often encountered by dermatologists, and it is driven by factors such as mild symptoms and cost-saving. This study aims to assess the prevalence of self-prescription of Vitamin-A analogs and awareness of their adverse effects among the general population.
Methods: An online questionnaire was formulated by the research team through an extensive literature review and was validated by three experts in dermatology. It was distributed and collected from the five regions in Saudi Arabia.
Results: The present study included 2150 participants, primarily female (76.3%), aged 18-24 (50.6%), and over 60% holding bachelor’s degrees. Social media (29.5%) and physicians (26.2%) were common sources of information about Vitamin A analogs for acne treatment. Nearly half had been diagnosed with acne, and 42.5% were aware of adverse effects, with dryness being the most reported (59.7%). Acretin (28.1%) was the most used medication. Awareness of avoiding Vitamin A analogs during pregnancy was 47.0%. Sociodemographic factors such as age, region, and acne history were significantly associated with the awareness regarding Vitamin A use during pregnancy.
Conclusion: The present study revealed a substantial prevalence of self-prescribed Vitamin A analogs for acne, particularly among young, educated individuals. The high awareness of potential adverse effects underscores the need for improved education. Sociodemographic associations highlight the importance of targeted interventions in promoting safe practices.

Key words: Acne vulgaris, retinoids, self-prescription, vitamin A analogues


 
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How to Cite this Article
Pubmed Style

Alruwaili MS, Alahmadi MA, Alzanadi RH, Almughera TN, Almohsen DS, Bukhamsin SA, Alghamdi KM, Alhaqbani RM, Alsifri SS, Alqahtani RF, Alfalah HA, Alotaibi MK. Prevalence of self-prescribed Vitamin A analogs and awareness of related adverse effects. IJMDC. 2024; 8(6): 1403-1410. doi:10.24911/IJMDC.51-1711106265

Web Style

Alruwaili MS, Alahmadi MA, Alzanadi RH, Almughera TN, Almohsen DS, Bukhamsin SA, Alghamdi KM, Alhaqbani RM, Alsifri SS, Alqahtani RF, Alfalah HA, Alotaibi MK. Prevalence of self-prescribed Vitamin A analogs and awareness of related adverse effects. https://www.ijmdc.com/?mno=195122 [Access: May 15, 2025]. doi:10.24911/IJMDC.51-1711106265

AMA (American Medical Association) Style

Alruwaili MS, Alahmadi MA, Alzanadi RH, Almughera TN, Almohsen DS, Bukhamsin SA, Alghamdi KM, Alhaqbani RM, Alsifri SS, Alqahtani RF, Alfalah HA, Alotaibi MK. Prevalence of self-prescribed Vitamin A analogs and awareness of related adverse effects. IJMDC. 2024; 8(6): 1403-1410. doi:10.24911/IJMDC.51-1711106265


Vancouver/ICMJE Style

Alruwaili MS, Alahmadi MA, Alzanadi RH, Almughera TN, Almohsen DS, Bukhamsin SA, Alghamdi KM, Alhaqbani RM, Alsifri SS, Alqahtani RF, Alfalah HA, Alotaibi MK. Prevalence of self-prescribed Vitamin A analogs and awareness of related adverse effects. IJMDC. (2024), [cited May 15, 2025]; 8(6): 1403-1410. doi:10.24911/IJMDC.51-1711106265


Harvard Style

Alruwaili, M. S., Alahmadi, . M. A., Alzanadi, . R. H., Almughera, . T. N., Almohsen, . D. S., Bukhamsin, . S. A., Alghamdi, . K. M., Alhaqbani, . R. M., Alsifri, . S. S., Alqahtani, . R. F., Alfalah, . H. A. & Alotaibi, . M. K. (2024) Prevalence of self-prescribed Vitamin A analogs and awareness of related adverse effects. IJMDC, 8 (6), 1403-1410. doi:10.24911/IJMDC.51-1711106265


Turabian Style

Alruwaili, Maram S., Mohammed A. Alahmadi, Rabab H. Alzanadi, Tharaa N. Almughera, Danyah S. Almohsen, Sarah A. Bukhamsin, Kholoud M. Alghamdi, Renad M. Alhaqbani, Sahar S. Alsifri, Reemah F. Alqahtani, Haifa A. Alfalah, and Moteb K. Alotaibi. 2024. Prevalence of self-prescribed Vitamin A analogs and awareness of related adverse effects. International Journal of Medicine in Developing Countries, 8 (6), 1403-1410. doi:10.24911/IJMDC.51-1711106265


Chicago Style

Alruwaili, Maram S., Mohammed A. Alahmadi, Rabab H. Alzanadi, Tharaa N. Almughera, Danyah S. Almohsen, Sarah A. Bukhamsin, Kholoud M. Alghamdi, Renad M. Alhaqbani, Sahar S. Alsifri, Reemah F. Alqahtani, Haifa A. Alfalah, and Moteb K. Alotaibi. "Prevalence of self-prescribed Vitamin A analogs and awareness of related adverse effects." International Journal of Medicine in Developing Countries 8 (2024), 1403-1410. doi:10.24911/IJMDC.51-1711106265


MLA (The Modern Language Association) Style

Alruwaili, Maram S., Mohammed A. Alahmadi, Rabab H. Alzanadi, Tharaa N. Almughera, Danyah S. Almohsen, Sarah A. Bukhamsin, Kholoud M. Alghamdi, Renad M. Alhaqbani, Sahar S. Alsifri, Reemah F. Alqahtani, Haifa A. Alfalah, and Moteb K. Alotaibi. "Prevalence of self-prescribed Vitamin A analogs and awareness of related adverse effects." International Journal of Medicine in Developing Countries 8.6 (2024), 1403-1410. Print. doi:10.24911/IJMDC.51-1711106265


APA (American Psychological Association) Style

Alruwaili, M. S., Alahmadi, . M. A., Alzanadi, . R. H., Almughera, . T. N., Almohsen, . D. S., Bukhamsin, . S. A., Alghamdi, . K. M., Alhaqbani, . R. M., Alsifri, . S. S., Alqahtani, . R. F., Alfalah, . H. A. & Alotaibi, . M. K. (2024) Prevalence of self-prescribed Vitamin A analogs and awareness of related adverse effects. International Journal of Medicine in Developing Countries, 8 (6), 1403-1410. doi:10.24911/IJMDC.51-1711106265




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