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2024, Vol: 8, Issue: 11
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Review Article
Online Published: 31 Jul 2023
 


Utilizing mesenchymal stem cells to improve the healing process of the medial collateral ligament in the knee

Basem Ali Zogel, Hussam Masoud Darraj, Zenat Ahmed Khired, Fahad Yahya Alarishi.


Abstract
The healing process of the medial collateral ligament (MCL) in the knee is often slow, resulting in adverse outcomes such as scar tissue formation, joint instability, limited range of motion, and an increased risk of re-injury. Consequently, novel therapeutic strategies are imperative to enhance MCL healing. Mesenchymal stem cells (MSCs) have emerged as a promising treatment modality due to their robust proliferative ability, reparative potential, and ability to differentiate into various cell types. Although preclinical studies have shown encouraging results for MSC-based approaches in MCL injuries, clinical studies in the orthopedic literature remain scarce. This review provides an overview of the MCL, conventional treatments for MCL injuries, and recent advances in MSC research for augmenting MCL healing. MSC-based approaches hold promise as a future therapeutic option to improve MCL healing. Nonetheless, further research is warranted to establish the effective ness and safety of this emerging treatment modality.

Key words: : Medial collateral ligament (MCL), mesenchymal stem cells (MSCs), healing, injury.


 
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How to Cite this Article
Pubmed Style

Zogel BA, Darraj HM, Khired ZA, Alarishi FY. Utilizing mesenchymal stem cells to improve the healing process of the medial collateral ligament in the knee. IJMDC. 2023; 7(11): 1515-1519. doi:10.24911/IJMDC.51-1687420913

Web Style

Zogel BA, Darraj HM, Khired ZA, Alarishi FY. Utilizing mesenchymal stem cells to improve the healing process of the medial collateral ligament in the knee. https://www.ijmdc.com/?mno=158488 [Access: January 15, 2025]. doi:10.24911/IJMDC.51-1687420913

AMA (American Medical Association) Style

Zogel BA, Darraj HM, Khired ZA, Alarishi FY. Utilizing mesenchymal stem cells to improve the healing process of the medial collateral ligament in the knee. IJMDC. 2023; 7(11): 1515-1519. doi:10.24911/IJMDC.51-1687420913


Vancouver/ICMJE Style

Zogel BA, Darraj HM, Khired ZA, Alarishi FY. Utilizing mesenchymal stem cells to improve the healing process of the medial collateral ligament in the knee. IJMDC. (2023), [cited January 15, 2025]; 7(11): 1515-1519. doi:10.24911/IJMDC.51-1687420913


Harvard Style

Zogel, B. A., Darraj, . H. M., Khired, . Z. A. & Alarishi, . F. Y. (2023) Utilizing mesenchymal stem cells to improve the healing process of the medial collateral ligament in the knee. IJMDC, 7 (11), 1515-1519. doi:10.24911/IJMDC.51-1687420913


Turabian Style

Zogel, Basem Ali, Hussam Masoud Darraj, Zenat Ahmed Khired, and Fahad Yahya Alarishi. 2023. Utilizing mesenchymal stem cells to improve the healing process of the medial collateral ligament in the knee. International Journal of Medicine in Developing Countries, 7 (11), 1515-1519. doi:10.24911/IJMDC.51-1687420913


Chicago Style

Zogel, Basem Ali, Hussam Masoud Darraj, Zenat Ahmed Khired, and Fahad Yahya Alarishi. "Utilizing mesenchymal stem cells to improve the healing process of the medial collateral ligament in the knee." International Journal of Medicine in Developing Countries 7 (2023), 1515-1519. doi:10.24911/IJMDC.51-1687420913


MLA (The Modern Language Association) Style

Zogel, Basem Ali, Hussam Masoud Darraj, Zenat Ahmed Khired, and Fahad Yahya Alarishi. "Utilizing mesenchymal stem cells to improve the healing process of the medial collateral ligament in the knee." International Journal of Medicine in Developing Countries 7.11 (2023), 1515-1519. Print. doi:10.24911/IJMDC.51-1687420913


APA (American Psychological Association) Style

Zogel, B. A., Darraj, . H. M., Khired, . Z. A. & Alarishi, . F. Y. (2023) Utilizing mesenchymal stem cells to improve the healing process of the medial collateral ligament in the knee. International Journal of Medicine in Developing Countries, 7 (11), 1515-1519. doi:10.24911/IJMDC.51-1687420913




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