E-ISSN 1658-7820
 

Review Article

Online Publishing Date:
01 / 03 / 2024

 


The Role of Low Molecular-Weight Heparin on Recurrent Abortion: a review

Taraji Saeed Alrehaili, Mohamed Abdulrahman Alnajjar, Mohammed Saeed Alrehaili, Abdulellah Ismail Alqurashi, Muhammad Essam Aldabbagh.


Abstract
Recurrent abortion (RA) remains a significant challenge in gynecological practice. It is not only emotionally devastating for pregnant women but is also medically challenging. RA is the spontaneous loss in the first trimester of three or more consecutive pregnancies. The current review was aimed at investigating the role of low molecular weight heparin (LMWH) in recurrent abortion. The online databases MEDLINE and Google Scholar were used to perform a literature search for publications published between 2015 and 2013, without any date or language restrictions. We used a combination of relevant search terms “role, low, molecular, weight, heparin, recurrent, and abortion”. We independently identified publications and systematically screened titles, abstracts, and full texts of the collected publications. LMWH was found being used to treat recurrent abortion due to its anticoagulants and anti-inflammatory effect. Its use is associated with a substantial improvement in live birth rates in most studies reviewed, with a few inconclusive. There was no significant improvement in late pregnancy complications in women treated with LMWH in the control group. Women treated with LMWH experienced very few adverse medication responses, and those that did occur were often moderate and self-limiting, making LMWH therapy a safe option. To create a consensus recommendation on the treatment of recurrent abortion, further research on the use of LMWH is required, ideally in the form of sizable multicenter randomized control trials.

Key words: Role, low, molecular, weight, heparin, recurrent, abortion.


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Taraji Saeed Alrehaili
Articles by Mohamed Abdulrahman Alnajjar
Articles by Mohammed Saeed Alrehaili
Articles by Abdulellah Ismail Alqurashi
Articles by Muhammad Essam Aldabbagh
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Alrehaili TS, Alnajjar MA, Alrehaili MS, Alqurashi AI, Aldabbagh ME. The Role of Low Molecular-Weight Heparin on Recurrent Abortion: a review. IJMDC. Online First: 01 Mar, 2024. doi:10.24911/IJMDC.51-1705268912


Web Style

Alrehaili TS, Alnajjar MA, Alrehaili MS, Alqurashi AI, Aldabbagh ME. The Role of Low Molecular-Weight Heparin on Recurrent Abortion: a review. https://www.ijmdc.com/?mno=185327 [Access: March 26, 2024]. doi:10.24911/IJMDC.51-1705268912


AMA (American Medical Association) Style

Alrehaili TS, Alnajjar MA, Alrehaili MS, Alqurashi AI, Aldabbagh ME. The Role of Low Molecular-Weight Heparin on Recurrent Abortion: a review. IJMDC. Online First: 01 Mar, 2024. doi:10.24911/IJMDC.51-1705268912



Vancouver/ICMJE Style

Alrehaili TS, Alnajjar MA, Alrehaili MS, Alqurashi AI, Aldabbagh ME. The Role of Low Molecular-Weight Heparin on Recurrent Abortion: a review. IJMDC, [cited March 26, 2024]; Online First: 01 Mar, 2024. doi:10.24911/IJMDC.51-1705268912



Harvard Style

Alrehaili, T. S., Alnajjar, . M. A., Alrehaili, . M. S., Alqurashi, . A. I. & Aldabbagh, . M. E. (2024) The Role of Low Molecular-Weight Heparin on Recurrent Abortion: a review. IJMDC, Online First: 01 Mar, 2024. doi:10.24911/IJMDC.51-1705268912



Turabian Style

Alrehaili, Taraji Saeed, Mohamed Abdulrahman Alnajjar, Mohammed Saeed Alrehaili, Abdulellah Ismail Alqurashi, and Muhammad Essam Aldabbagh. 2024. The Role of Low Molecular-Weight Heparin on Recurrent Abortion: a review. International Journal of Medicine in Developing Countries, Online First: 01 Mar, 2024. doi:10.24911/IJMDC.51-1705268912



Chicago Style

Alrehaili, Taraji Saeed, Mohamed Abdulrahman Alnajjar, Mohammed Saeed Alrehaili, Abdulellah Ismail Alqurashi, and Muhammad Essam Aldabbagh. "The Role of Low Molecular-Weight Heparin on Recurrent Abortion: a review." International Journal of Medicine in Developing Countries Online First: 01 Mar, 2024. doi:10.24911/IJMDC.51-1705268912



MLA (The Modern Language Association) Style

Alrehaili, Taraji Saeed, Mohamed Abdulrahman Alnajjar, Mohammed Saeed Alrehaili, Abdulellah Ismail Alqurashi, and Muhammad Essam Aldabbagh. "The Role of Low Molecular-Weight Heparin on Recurrent Abortion: a review." International Journal of Medicine in Developing Countries Online First: 01 Mar, 2024. Web. 26 Mar 2024 doi:10.24911/IJMDC.51-1705268912



APA (American Psychological Association) Style

Alrehaili, T. S., Alnajjar, . M. A., Alrehaili, . M. S., Alqurashi, . A. I. & Aldabbagh, . M. E. (2024) The Role of Low Molecular-Weight Heparin on Recurrent Abortion: a review. International Journal of Medicine in Developing Countries, Online First: 01 Mar, 2024. doi:10.24911/IJMDC.51-1705268912





Most Viewed Articles
Most Accessed Articles

  • Marginal adaptation of fixed prosthodontics
    Shahad Mohammed Halawani, Sahar Amer Al-Harbi
    IJMDC. 2017; 1(2): 78-84
    » Abstract » doi: 10.24911/IJMDC.1.2.7

  • Parasites in central nervous system
    Amal Ahmed Mohamed, Asmaa Mohamed Mansour
    IJMDC. 2017; 1(2): 72-77
    » Abstract » doi: 10.24911/IJMDC.1.2.6

  • Non-diabetic retinopathy: a case report
    Hassan F. Alkwikbi, Nabil Mamon Abdelfattah, Haithem Mamon Abdelfattah
    IJMDC. 2017; 1(1): 33-37
    » Abstract » doi: 10.24911/IJMDC.1.1.6

  • Vitamin D deficiency among high school female students in Riyadh
    Sahar Mohsen Aldhafeeri, Fatemah Ibraheem Alrawaji, Abrar Mubarak Algharbi, Alanoud Abdullah Alhessan, Ayat Sami Qabaja, Ghaleah Abdulaziz Alnassar, Ghaliah Ofayn Alsulami, Mashael Belal Alrubaian, Norah Abdulaziz Alhatim, Salehah Salih Alotaibi, Zahra Ali Alkhamees
    IJMDC. 2017; 1(1): 18-23
    » Abstract » doi: 10.24911/IJMDC.1.1.4

  • Prognosis of chronic complications of diabetes mellitus (DM) after multiple events of diabetic ketoacidosis (DKA)
    Baraa Faiez Rajab, Anwar Essa Alamrim, Ali Essa Alamri
    IJMDC. 2019; 3(5): 474-479
    » Abstract » doi: 10.24911/IJMDC.51-1546551993

  • Most Downloaded
    Top Downloaded Articles

  • Anti-IL-17 markedly inhibited the in vitro granuloma induced by Schistosoma mansoni soluble egg antigen.
    Asmaa Ezz, Irene S. Gmail, Fatma Elzahraa H. Salem, Rabab Salama, Soad Nady
    IJMDC. 2018; 2(January 2018): 38-46
    » Abstract » doi: 10.24911/IJMDC.2.1.7

  • Vitamin D deficiency among high school female students in Riyadh
    Sahar Mohsen Aldhafeeri, Fatemah Ibraheem Alrawaji, Abrar Mubarak Algharbi, Alanoud Abdullah Alhessan, Ayat Sami Qabaja, Ghaleah Abdulaziz Alnassar, Ghaliah Ofayn Alsulami, Mashael Belal Alrubaian, Norah Abdulaziz Alhatim, Salehah Salih Alotaibi, Zahra Ali Alkhamees
    IJMDC. 2017; 1(1): 18-23
    » Abstract » doi: 10.24911/IJMDC.1.1.4

  • Antibiotic Resistance Crisis
    Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
    IJMDC. 2019; 3(6): 561-564
    » Abstract » doi: 10.24911/IJMDC.51-1549060699

  • The knowledge of mothers about children malnutrition and associated factors
    Anas Abdulrahman Aljohani, Mujahid Abdulrahman Aljohani
    IJMDC. 2020; 4(1): 7-11
    » Abstract » doi: 10.24911/IJMDC.51-1541620358

  • Knowledge and attitude of caregivers of cerebral palsy children in Riyadh city
    Abdulaziz Alruwaished, Baleegh Ali, Lubna Abdullah Alhowaimil , Abaraa adullah Alhowaimil, Najd Abdullah Alhowaimil, Aminah Alessa
    IJMDC. 2020; 4(1): 12-17
    » Abstract » doi: 10.24911/IJMDC.51-1547833051

  • Most Cited Articles
    Most Cited Articles

  • Antibiotic Resistance Crisis
    Nuha Saad Mobarki, Buthaina Abdullah Almerabi, Ahmad Hattan Hattan
    IJMDC. 2019; 3(6): 561-564
    » Abstract » doi: 10.24911/IJMDC.51-1549060699
    Cited : 34 times [Click to see citing articles]

  • Prevalence of depression, anxiety and stress among diabetes mellitus patients in Arar, Northern Saudi Arabia
    AMohammed Elamin Mukrim, Nujud Muteb D. Alshammari, Wurud Muteb D. Alshammari, Maali Subhi T. Alshammari, Yousef Nasif R. Alshammari, Abdulaziz Sael M. Alshammari, Maisa Hamad F. Alanazi, Abdulelah Abdulrhman F. Alzammam, Muharib Mana M. Alshammari, Slwa Khaled Abu Asyah, Aseel Jamal Alzuhayri, Mushref Saeid Alshammari
    IJMDC. 2019; 3(3): 229-233
    » Abstract » doi: 10.24911/IJMDC.51-1542576396
    Cited : 8 times [Click to see citing articles]

  • Knowledge, attitude, and practice of breast self-examination toward breast cancer among female students at King Saud University in Riyadh, Saudi Arabia
    Abdullah Nasser Alomair, Dania Ghazi Felemban, Mohannad Sami Felemban, Jameel Abdullah Awadain, Ammar Saud Altowairqi, Nawaf Fawzan Alfawzan, Fatimah Mohammed Almazayen, Abdulrahman Jalwi Korkoman, Nawaf Saad Alrusayyis
    IJMDC. 2020; 4(2): 429-434
    » Abstract » doi: 10.24911/IJMDC.51-1576668182
    Cited : 8 times [Click to see citing articles]

  • Population awareness about rheumatoid arthritis in Jazan region, Saudi Arabia
    Ahmad Ali Hazzazi, Mohssen Hassen Ageeli, Ahmed Ali Muyidi, Abdulaziz Mohammad Abulgasim, Abdullah Ahmad Yateemi, Nabil Alhakami
    IJMDC. 2020; 4(3): 668-675
    » Abstract » doi: 10.24911/IJMDC.51-1576010943
    Cited : 4 times [Click to see citing articles]

  • Prevalence and factors associated with depression among health care workers in National Guard Hospital in Riyadh, KSA
    Noor Mohammad AlFahhad
    IJMDC. 2018; 2(September 2018): 92-96
    » Abstract » doi: 10.24911/IJMDC.51-1526306040
    Cited : 4 times [Click to see citing articles]