E-ISSN 1658-7820
 

Review Article 


Association between Liraglutide (Saxenda (R)) and weight reduction; a systematic review

Arwa Ahmed AlQahtani, Nouf Marzuk Almutairi, Alhanoof Wajap Alotaibi, Wejdan Mohammed Awn Allah Almutairi, Areej Jamaan Al Ghamdi.


Abstract
Background: Obesity is one of the most common conditions, especially in developing countries. Many medications have been proposed to have a positive impact on body weight, yet their safety profile was a barrier against their use. Liraglutide is one of the medications that have a weight reduction potential. However, data about its safety and effectiveness in weight reduction is conflicting. Objective: This study aims at examining the medical literature to evaluate the correlation between using Liraglutide and weight reduction. Method: the literature was reviewed through Medline, PubMed, Embase, and Ovid database in the duration between 2009 and 2019. Searching terms included were a combination of "Association" AND "Liraglutide" AND "weight reduction". Following this, results were filtered to include only original research articles investigating weight reduction accompanying the administration of Liraglutide. Selected trials mentioned the target population and any adjunctive intervention or treatment to Liraglutide. Result: A total of 1904 articles were retrieved. Following the exclusion of articles on animals and including only trials on humans, 42 articles appeared. A total of eight articles were identified as eligible, covering a total of 6406 patients with overweight or obesity. All the studies were randomized, blinded studies, except for one study, was observational. Conclusion: Liraglutide showed to be an effective medication in reducing body weight if taken for short term or long term. Hypoglycemia occurring with Liraglutide was minimal.

Key words: Liraglutide, diabetes mellitus, weight loss, review


 
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How to Cite this Article
Pubmed Style

AlQahtani AA, Almutairi NM, Alotaibi AW, Almutairi WMAA, Ghamdi AJA. Association between Liraglutide (Saxenda (R)) and weight reduction; a systematic review. doi:10.24911/IJMDC.51-1576580920


Web Style

AlQahtani AA, Almutairi NM, Alotaibi AW, Almutairi WMAA, Ghamdi AJA. Association between Liraglutide (Saxenda (R)) and weight reduction; a systematic review. https://www.ijmdc.com/?mno=78342 [Access: March 26, 2024]. doi:10.24911/IJMDC.51-1576580920


AMA (American Medical Association) Style

AlQahtani AA, Almutairi NM, Alotaibi AW, Almutairi WMAA, Ghamdi AJA. Association between Liraglutide (Saxenda (R)) and weight reduction; a systematic review. doi:10.24911/IJMDC.51-1576580920



Vancouver/ICMJE Style

AlQahtani AA, Almutairi NM, Alotaibi AW, Almutairi WMAA, Ghamdi AJA. Association between Liraglutide (Saxenda (R)) and weight reduction; a systematic review. doi:10.24911/IJMDC.51-1576580920



Harvard Style

AlQahtani, A. A., Almutairi, . N. M., Alotaibi, . A. W., Almutairi, . W. M. A. A. & Ghamdi, . A. J. A. (2019) Association between Liraglutide (Saxenda (R)) and weight reduction; a systematic review. doi:10.24911/IJMDC.51-1576580920



Turabian Style

AlQahtani, Arwa Ahmed, Nouf Marzuk Almutairi, Alhanoof Wajap Alotaibi, Wejdan Mohammed Awn Allah Almutairi, and Areej Jamaan Al Ghamdi. 2019. Association between Liraglutide (Saxenda (R)) and weight reduction; a systematic review. doi:10.24911/IJMDC.51-1576580920



Chicago Style

AlQahtani, Arwa Ahmed, Nouf Marzuk Almutairi, Alhanoof Wajap Alotaibi, Wejdan Mohammed Awn Allah Almutairi, and Areej Jamaan Al Ghamdi. "Association between Liraglutide (Saxenda (R)) and weight reduction; a systematic review." doi:10.24911/IJMDC.51-1576580920



MLA (The Modern Language Association) Style

AlQahtani, Arwa Ahmed, Nouf Marzuk Almutairi, Alhanoof Wajap Alotaibi, Wejdan Mohammed Awn Allah Almutairi, and Areej Jamaan Al Ghamdi. "Association between Liraglutide (Saxenda (R)) and weight reduction; a systematic review." doi:10.24911/IJMDC.51-1576580920



APA (American Psychological Association) Style

AlQahtani, A. A., Almutairi, . N. M., Alotaibi, . A. W., Almutairi, . W. M. A. A. & Ghamdi, . A. J. A. (2019) Association between Liraglutide (Saxenda (R)) and weight reduction; a systematic review. doi:10.24911/IJMDC.51-1576580920





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