Abstract
Myocardial infraction (MI) is a fatal subset of acute coronary syndrome, where the cardiac muscle is damaged, and an increased cardiac troponin level is observed due to acute ischemia. The management of MI in an earlier stage would give a great advantage for disease management. We aim to systematically assess the literature on the outcomes of MI intervention and its efficiency besides indicating the risk factors of MI itself and risk factors, which leads to the failure of MI interventions. A comprehensive electronic search with time and language restrictions was conducted. Several known databases were included: "Google Scholar, PubMed, the Cochrane Library, and Web of Science," targeting articles published between 2015 and 2020. We combined the search terms and limited the study to the English language. Depending on the PRISMA checklist, we removed duplicates; the articles were then screened based on title, abstract, and full text. A literature review was conducted, resulting in 3,564 hits, which, after removing duplicates and articles that did not fit the inclusion criteria, ended in 11 studies (three retrospective studies, five prospective studies, one randomized clinical trial, one descriptive study, and one cross-sectional study). The whole review reported 10,602 cases, of which 8,393 were male (79.2%), and 2209 were female (20.8%), with an average age of 59.5 years. This study demonstrated the safety and efficiency of using pharmacoinvasive therapy in the treatment of MI when primary percutaneous coronary angioplasty was not available. The level of awareness among the public was found inadequate, especially regarding the MI risk factors. We recommend further investigations to understand better why some factors could affect the outcomes of these interventions.

Key words: MI, intervention, risk factors, PMI, pharmacoinvasive, treatment, awareness, PPCI