E-ISSN 1658-7820
 

Original Article

Online Publishing Date:
17 / 05 / 2020

 


Correlation Between Technetium-99msestamibi Scans, Intraoperative Findings, and Histopathological Results in Primary and Tertiary Hyperparathyroidism

Abdullah Thawabeh, Sara Assiri, Shroog Alharthi.


Abstract
Background: Technetium sestamibi imaging focuses on detecting adenomas in primary hyperparathyroidism patients scheduled for parathyroidectomy with unilateral neck exploration. However, its role in the primary resection of tertiary hyperparathyroidism patients is not yet well-defined. This study aims to analyze all data of primary and tertiary hyperparathyroidism patients who underwent parathyroidectomy after the preoperative sestamibi scan. Methodology: A cross-sectional study involved a total of 28 primary and tertiary hyperparathyroidism patients who underwent 99Tc sestamibi imaging before performing parathyroidectomy from January of 2016 to August of 2018. Data collection also involved intraoperative and histopathological findings, and preoperative biochemical values and post-operative calcium levels. Results: A total of 28 patients with a mean age of 53.89 + 14 years and a female predominance (92.9%) were included. In primary hyperparathyroidism, patients 90.5% had true positive sestamibi results and 22.2% had false-positive results, while in tertiary hyperparathyroidism patients, only 9.5% had true positive sestamibi results and 44.4% had false-positive results. Those who underwent unilateral exploration had a mean postoperative calcium level of 2.28+0.21 mmol/l, while those who underwent bilateral neck exploration showed a mean postoperative calcium level of 2.01+ 2.44 mmol/l. Conclusion: Sestamibi scanning is a highly beneficial imaging technique for localizing adenomas in primary hyperparathyroidism patients. This method can facilitate unilateral surgical approach and was found to decrease postoperative hypocalcemia. However, the usefulness of sestamibi scans in the primary resection of tertiary hyperparathyroidism patients is limited, and it does not have any significance in changing the surgical approach.

Key words: Hyperparathyroidism, sestamibi scan, adenoma, Saudi Arabia, parathyroidectomy.


 
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How to Cite this Article
Pubmed Style

Thawabeh A, Assiri S, Alharthi S. Correlation Between Technetium-99msestamibi Scans, Intraoperative Findings, and Histopathological Results in Primary and Tertiary Hyperparathyroidism. IJMDC. 2020; 4(6): 968-974. doi:10.24911/IJMDC.51-1586902477


Web Style

Thawabeh A, Assiri S, Alharthi S. Correlation Between Technetium-99msestamibi Scans, Intraoperative Findings, and Histopathological Results in Primary and Tertiary Hyperparathyroidism. https://www.ijmdc.com/?mno=99368 [Access: March 27, 2024]. doi:10.24911/IJMDC.51-1586902477


AMA (American Medical Association) Style

Thawabeh A, Assiri S, Alharthi S. Correlation Between Technetium-99msestamibi Scans, Intraoperative Findings, and Histopathological Results in Primary and Tertiary Hyperparathyroidism. IJMDC. 2020; 4(6): 968-974. doi:10.24911/IJMDC.51-1586902477



Vancouver/ICMJE Style

Thawabeh A, Assiri S, Alharthi S. Correlation Between Technetium-99msestamibi Scans, Intraoperative Findings, and Histopathological Results in Primary and Tertiary Hyperparathyroidism. IJMDC. (2020), [cited March 27, 2024]; 4(6): 968-974. doi:10.24911/IJMDC.51-1586902477



Harvard Style

Thawabeh, A., Assiri, . S. & Alharthi, . S. (2020) Correlation Between Technetium-99msestamibi Scans, Intraoperative Findings, and Histopathological Results in Primary and Tertiary Hyperparathyroidism. IJMDC, 4 (6), 968-974. doi:10.24911/IJMDC.51-1586902477



Turabian Style

Thawabeh, Abdullah, Sara Assiri, and Shroog Alharthi. 2020. Correlation Between Technetium-99msestamibi Scans, Intraoperative Findings, and Histopathological Results in Primary and Tertiary Hyperparathyroidism. International Journal of Medicine in Developing Countries, 4 (6), 968-974. doi:10.24911/IJMDC.51-1586902477



Chicago Style

Thawabeh, Abdullah, Sara Assiri, and Shroog Alharthi. "Correlation Between Technetium-99msestamibi Scans, Intraoperative Findings, and Histopathological Results in Primary and Tertiary Hyperparathyroidism." International Journal of Medicine in Developing Countries 4 (2020), 968-974. doi:10.24911/IJMDC.51-1586902477



MLA (The Modern Language Association) Style

Thawabeh, Abdullah, Sara Assiri, and Shroog Alharthi. "Correlation Between Technetium-99msestamibi Scans, Intraoperative Findings, and Histopathological Results in Primary and Tertiary Hyperparathyroidism." International Journal of Medicine in Developing Countries 4.6 (2020), 968-974. Print. doi:10.24911/IJMDC.51-1586902477



APA (American Psychological Association) Style

Thawabeh, A., Assiri, . S. & Alharthi, . S. (2020) Correlation Between Technetium-99msestamibi Scans, Intraoperative Findings, and Histopathological Results in Primary and Tertiary Hyperparathyroidism. International Journal of Medicine in Developing Countries, 4 (6), 968-974. doi:10.24911/IJMDC.51-1586902477





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