Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia

Mohammed S Alzahrani; Riyadh M Alloqmani; Mohammed H Alharbi; Mohammed A Allihyani; Mohammad M Alofi; Abdulrahman M Alganawi; Saleh M Alloqmani; Sultan S Alam; Ahmed A Alzahrani

doi:10.24911/IJMDC.51-1577581131

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Original Article

Online Publishing Date:
26 / 01 / 2020

IJMDC. 2020; 4(3): 695-699

doi: 10.24911/IJMDC.51-1577581131

Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia

Mohammed S Alzahrani, Riyadh M Alloqmani, Mohammed H Alharbi, Mohammed A Allihyani, Mohammad M Alofi, Abdulrahman M Alganawi, Saleh M Alloqmani, Sultan S Alam, Ahmed A Alzahrani.

Abstract
Background: Dengue fever (DF) affects approximately 390 million every year, of which 96 million manifests clinically. This study aims to explore the common clinical presentations and laboratory findings of DF with the outcome of hospitalized patients at King Abdulaziz medical city in Jeddah.
Methodology: An observational cross-sectional study was carried which includes adults 18 years and older who were serologically confirmed the cases of DF and fulfilled the inclusion and exclusion criteria. Data were retrieved by using the electronic clinical information system (BestCare) and electronic laboratory information system (CERNER) at King Abdulaziz Medical City in Jeddah from Jan 2012 to Dec 2017.
Results: A total of 110 patients were studied, 64 (58.2%) were males and 46 (41.8%) were females, 107 (97.3%) were Saudis and 3 (2.7%) patients were non-Saudis with a median age of 39-year old. Serology tests showed six different patterns of the 110 patients. The most common serology pattern was IgM and IgG positive. The most common clinical presentations were fever (107 patients 97.3%), headache (78 patients 70.9%), myalgia (69 patients 62.7%), vomiting (39 patients 35.5%), and nausea (25 patients 22.7%). The most common lab findings were thrombocytopenia (86 patients), leucopenia (86 patients), aspartate aminotransferase was elevated in 72 patients, and alanine aminotransferase (ALT) was elevated in 61 patients. 106 patients were diagnosed with DF, 3 patients diagnosed with hemorrhagic fever, and only 2 patients were diagnosed with dengue shock one of them was admitted to intensive care unit. Regarding the comorbidities, 30 patients were diabetic and 1 patient was pregnant.
Conclusion: Fever and thrombocytopenia were the most common clinical and laboratory findings, while confusion and bleeding were the least findings. The overall mortality of DF was found low.

Key words: Dengue fever, dengue manifestation, dengue hemorrhagic, dengue shock, clinical profile, Nonstructural protein 1

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Pubmed Style

Alzahrani MS, Alloqmani RM, Alharbi MH, Allihyani MA, Alofi MM, Alganawi AM, Alloqmani SM, Alam SS, Alzahrani AA. Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. IJMDC. 2020; 4(3): 695-699. doi:10.24911/IJMDC.51-1577581131

Web Style

Alzahrani MS, Alloqmani RM, Alharbi MH, Allihyani MA, Alofi MM, Alganawi AM, Alloqmani SM, Alam SS, Alzahrani AA. Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. https://www.ijmdc.com/?mno=79806 [Access: March 26, 2024]. doi:10.24911/IJMDC.51-1577581131

AMA (American Medical Association) Style

Alzahrani MS, Alloqmani RM, Alharbi MH, Allihyani MA, Alofi MM, Alganawi AM, Alloqmani SM, Alam SS, Alzahrani AA. Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. IJMDC. 2020; 4(3): 695-699. doi:10.24911/IJMDC.51-1577581131

Vancouver/ICMJE Style

Alzahrani MS, Alloqmani RM, Alharbi MH, Allihyani MA, Alofi MM, Alganawi AM, Alloqmani SM, Alam SS, Alzahrani AA. Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. IJMDC. (2020), [cited March 26, 2024]; 4(3): 695-699. doi:10.24911/IJMDC.51-1577581131

Harvard Style

Alzahrani, M. S., Alloqmani, . R. M., Alharbi, . M. H., Allihyani, . M. A., Alofi, . M. M., Alganawi, . A. M., Alloqmani, . S. M., Alam, . S. S. & Alzahrani, . A. A. (2020) Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. IJMDC, 4 (3), 695-699. doi:10.24911/IJMDC.51-1577581131

Turabian Style

Alzahrani, Mohammed S, Riyadh M Alloqmani, Mohammed H Alharbi, Mohammed A Allihyani, Mohammad M Alofi, Abdulrahman M Alganawi, Saleh M Alloqmani, Sultan S Alam, and Ahmed A Alzahrani. 2020. Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. International Journal of Medicine in Developing Countries, 4 (3), 695-699. doi:10.24911/IJMDC.51-1577581131

Chicago Style

Alzahrani, Mohammed S, Riyadh M Alloqmani, Mohammed H Alharbi, Mohammed A Allihyani, Mohammad M Alofi, Abdulrahman M Alganawi, Saleh M Alloqmani, Sultan S Alam, and Ahmed A Alzahrani. "Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia." International Journal of Medicine in Developing Countries 4 (2020), 695-699. doi:10.24911/IJMDC.51-1577581131

MLA (The Modern Language Association) Style

Alzahrani, Mohammed S, Riyadh M Alloqmani, Mohammed H Alharbi, Mohammed A Allihyani, Mohammad M Alofi, Abdulrahman M Alganawi, Saleh M Alloqmani, Sultan S Alam, and Ahmed A Alzahrani. "Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia." International Journal of Medicine in Developing Countries 4.3 (2020), 695-699. Print. doi:10.24911/IJMDC.51-1577581131

APA (American Psychological Association) Style

Alzahrani, M. S., Alloqmani, . R. M., Alharbi, . M. H., Allihyani, . M. A., Alofi, . M. M., Alganawi, . A. M., Alloqmani, . S. M., Alam, . S. S. & Alzahrani, . A. A. (2020) Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. International Journal of Medicine in Developing Countries, 4 (3), 695-699. doi:10.24911/IJMDC.51-1577581131

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