Original Article

IJMDC. 2020; 4(3): 695-699

Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia

Authors: Mohammed S Alzahrani, Riyadh M Alloqmani, Mohammed H Alharbi, Mohammed A Allihyani, Mohammad M Alofi, Abdulrahman M Alganawi, Saleh M Alloqmani, Sultan S Alam, Ahmed A Alzahrani.

ABSTRACT

Background: Dengue fever (DF) affects approximately 390 million every year, of which 96 million manifests clinically. This study aims to explore the common clinical presentations and laboratory findings of DF with the outcome of hospitalized patients at King Abdulaziz medical city in Jeddah. Methodology: An observational cross-sectional study was carried which includes adults 18 years and older who were serologically confirmed the cases of DF and fulfilled the inclusion and exclusion criteria. Data were retrieved by using the electronic clinical information system (BestCare) and electronic laboratory information system (CERNER) at King Abdulaziz Medical City in Jeddah from Jan 2012 to Dec 2017. Results: A total of 110 patients were studied, 64 (58.2%) were males and 46 (41.8%) were females, 107 (97.3%) were Saudis and 3 (2.7%) patients were non-Saudis with a median age of 39-year old. Serology tests showed six different patterns of the 110 patients. The most common serology pattern was IgM and IgG positive. The most common clinical presentations were fever (107 patients 97.3%), headache (78 patients 70.9%), myalgia (69 patients 62.7%), vomiting (39 patients 35.5%), and nausea (25 patients 22.7%). The most common lab findings were thrombocytopenia (86 patients), leucopenia (86 patients), aspartate aminotransferase was elevated in 72 patients, and alanine aminotransferase (ALT) was elevated in 61 patients. 106 patients were diagnosed with DF, 3 patients diagnosed with hemorrhagic fever, and only 2 patients were diagnosed with dengue shock one of them was admitted to intensive care unit. Regarding the comorbidities, 30 patients were diabetic and 1 patient was pregnant. Conclusion: Fever and thrombocytopenia were the most common clinical and laboratory findings, while confusion and bleeding were the least findings. The overall mortality of DF was found low.

Keywords:
Dengue fever, dengue manifestation, dengue hemorrhagic, dengue shock, clinical profile, Nonstructural protein 1


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Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia


Authors
Mohammed S Alzahrani
King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Riyadh M Alloqmani
Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia
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Mohammed H Alharbi
College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia
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Mohammed A Allihyani
College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia
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Mohammad M Alofi
College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia
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Abdulrahman M Alganawi
College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia
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Saleh M Alloqmani
College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia
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Sultan S Alam
College of Medicine, Umm Al-Qura University, Makkah, Saudia Arabia
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Ahmed A Alzahrani
College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia
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Correspondence to:
. King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Jeddah, Saudi Arabia; zahranim01@ngha.med.sa

Publication history
Received 29 Dec 2019
Accepted 09 Jan 2020
Published online 26 Jan 2020
Published in print 25 Feb 2020

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Pubmed Style

Alzahrani MS, Alloqmani RM, Alharbi MH, Allihyani MA, Alofi MM, Alganawi AM, Alloqmani SM, Alam SS, Alzahrani AA. Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. IJMDC. 2020; 4(3): 695-699. doi:10.24911/IJMDC.51-1577581131


Web Style

Alzahrani MS, Alloqmani RM, Alharbi MH, Allihyani MA, Alofi MM, Alganawi AM, Alloqmani SM, Alam SS, Alzahrani AA. Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. http://www.ijmdc.com/?mno=79806 [Access: March 28, 2020]. doi:10.24911/IJMDC.51-1577581131


AMA (American Medical Association) Style

Alzahrani MS, Alloqmani RM, Alharbi MH, Allihyani MA, Alofi MM, Alganawi AM, Alloqmani SM, Alam SS, Alzahrani AA. Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. IJMDC. 2020; 4(3): 695-699. doi:10.24911/IJMDC.51-1577581131


Vancouver/ICMJE Style

Alzahrani MS, Alloqmani RM, Alharbi MH, Allihyani MA, Alofi MM, Alganawi AM, Alloqmani SM, Alam SS, Alzahrani AA. Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. IJMDC. (2020), [cited March 28, 2020]; 4(3): 695-699. doi:10.24911/IJMDC.51-1577581131


Harvard Style

Alzahrani, M. S., Alloqmani, . R. M., Alharbi, . M. H., Allihyani, . M. A., Alofi, . M. M., Alganawi, . A. M., Alloqmani, . S. M., Alam, . S. S. & Alzahrani, . A. A. (2020) Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. IJMDC, 4 (3), 695-699. doi:10.24911/IJMDC.51-1577581131


Turabian Style

Alzahrani, Mohammed S, Riyadh M Alloqmani, Mohammed H Alharbi, Mohammed A Allihyani, Mohammad M Alofi, Abdulrahman M Alganawi, Saleh M Alloqmani, Sultan S Alam, and Ahmed A Alzahrani. 2020. Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. International Journal of Medicine in Developing Countries, 4 (3), 695-699. doi:10.24911/IJMDC.51-1577581131


Chicago Style

Alzahrani, Mohammed S, Riyadh M Alloqmani, Mohammed H Alharbi, Mohammed A Allihyani, Mohammad M Alofi, Abdulrahman M Alganawi, Saleh M Alloqmani, Sultan S Alam, and Ahmed A Alzahrani. "Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia." International Journal of Medicine in Developing Countries 4 (2020), 695-699. doi:10.24911/IJMDC.51-1577581131


MLA (The Modern Language Association) Style

Alzahrani, Mohammed S, Riyadh M Alloqmani, Mohammed H Alharbi, Mohammed A Allihyani, Mohammad M Alofi, Abdulrahman M Alganawi, Saleh M Alloqmani, Sultan S Alam, and Ahmed A Alzahrani. "Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia." International Journal of Medicine in Developing Countries 4.3 (2020), 695-699. Print. doi:10.24911/IJMDC.51-1577581131


APA (American Psychological Association) Style

Alzahrani, M. S., Alloqmani, . R. M., Alharbi, . M. H., Allihyani, . M. A., Alofi, . M. M., Alganawi, . A. M., Alloqmani, . S. M., Alam, . S. S. & Alzahrani, . A. A. (2020) Clinical and laboratory manifestations of dengue fever with the outcome of the hospitalized patients at King Abdulaziz Medical City in Jeddah, Saudi Arabia. International Journal of Medicine in Developing Countries, 4 (3), 695-699. doi:10.24911/IJMDC.51-1577581131


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