IJMDC. 2019; 3(1): 117-119

Proton-pump inhibitors use and risk of acute kidney injury

Authors: Majed Hassan Alghamdi, Yousef Ali Abdali, Jamilah Saleh Alyami, Hala Ahmed Aljohani, Majid Jobran Lughbi, Amnah Essa Abu Lahsah, Waleed Ali Fehran Alshehri, Nawal Ahmed Alshammari, Ali Omar Alshargi.

ABSTRACT

Acute interstitial nephritis associated with proton pump inhibitor is an immunologically mediated renal injury that is estimated to be one-quarter of the cases of acute kidney injury. Review of recent updates of the relationship between proton pump inhibitor use and development of interstitial nephritis in the period from 2008 to 2018 were included. Scientific websites were used to search for articles related to the subjects such as PubMed and Google scholar using several keywords including proton pump inhibitors, acute interstitial nephritis, adverse effects, and morbidity. 30 articles were obtained, 23 of them were included whereas the rest were excluded as their focus was different. Proton pump inhibitor-related interstitial nephritis is rare, quirky and challenging to suspect. It requires a high level of clinical prediction and knowledge. However, PPI use could be a risk factor for acute interstitial nephritis and should be administered carefully.

Keywords:
proton pump inhibitors, acute interstitial nephritis, adverse effects, and morbidity


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Proton-pump inhibitors use and risk of acute kidney injury


Authors
Majed Hassan Alghamdi
Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Yousef Ali Abdali
Faculty of Medicine, Jazan University, Jazan, Saudi Arabia
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Jamilah Saleh Alyami
Ibn Sina National College for Medical Studies, Jeddah, Saudi Arabia
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Hala Ahmed Aljohani
Ibn Sina National College for Medical Studies, Jeddah, Saudi Arabia
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Majid Jobran Lughbi
Faculty of Medicine, Jazan University, Jazan, Saudi Arabia
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Amnah Essa Abu Lahsah
Faculty of Medicine, Jazan University, Jazan, Saudi Arabia
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Waleed Ali Fehran Alshehri
King Khalid University, Abha, Saudi Arabia
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Nawal Ahmed Alshammari
Northern Border University, Arar, Saudi Arabia
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Ali Omar Alshargi
Ibn Sina National College for Medical Studies, Jeddah, Saudi Arabia
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Correspondence to:
. Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia; majed.h.s.alghamdi@gmail.com

Publication history
Published online 01 Jan 1970
Received 09 Dec 2018
Accepted 18 Dec 2018
Published in print 01 Feb 2019

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Pubmed Style

Alghamdi MH, Abdali YA, Alyami JS, Aljohani HA, Lughbi MJ, Lahsah AEA, Alshehri WAF, Alshammari NA, Alshargi AO. Proton-pump inhibitors use and risk of acute kidney injury. IJMDC. 2019; 3(1): 117-119. doi:10.24911/IJMDC.51-1544389362


Web Style

Alghamdi MH, Abdali YA, Alyami JS, Aljohani HA, Lughbi MJ, Lahsah AEA, Alshehri WAF, Alshammari NA, Alshargi AO. Proton-pump inhibitors use and risk of acute kidney injury. http://www.ijmdc.com/?mno=20921 [Access: July 23, 2019]. doi:10.24911/IJMDC.51-1544389362


AMA (American Medical Association) Style

Alghamdi MH, Abdali YA, Alyami JS, Aljohani HA, Lughbi MJ, Lahsah AEA, Alshehri WAF, Alshammari NA, Alshargi AO. Proton-pump inhibitors use and risk of acute kidney injury. IJMDC. 2019; 3(1): 117-119. doi:10.24911/IJMDC.51-1544389362


Vancouver/ICMJE Style

Alghamdi MH, Abdali YA, Alyami JS, Aljohani HA, Lughbi MJ, Lahsah AEA, Alshehri WAF, Alshammari NA, Alshargi AO. Proton-pump inhibitors use and risk of acute kidney injury. IJMDC. (2019), [cited July 23, 2019]; 3(1): 117-119. doi:10.24911/IJMDC.51-1544389362


Harvard Style

Alghamdi, M. H., Abdali, . Y. A., Alyami, . J. S., Aljohani, . H. A., Lughbi, . M. J., Lahsah, . A. E. A., Alshehri, . W. A. F., Alshammari, . N. A. & Alshargi, . A. O. (2019) Proton-pump inhibitors use and risk of acute kidney injury. IJMDC, 3 (1), 117-119. doi:10.24911/IJMDC.51-1544389362


Turabian Style

Alghamdi, Majed Hassan, Yousef Ali Abdali, Jamilah Saleh Alyami, Hala Ahmed Aljohani, Majid Jobran Lughbi, Amnah Essa Abu Lahsah, Waleed Ali Fehran Alshehri, Nawal Ahmed Alshammari, and Ali Omar Alshargi. 2019. Proton-pump inhibitors use and risk of acute kidney injury. International Journal of Medicine in Developing Countries, 3 (1), 117-119. doi:10.24911/IJMDC.51-1544389362


Chicago Style

Alghamdi, Majed Hassan, Yousef Ali Abdali, Jamilah Saleh Alyami, Hala Ahmed Aljohani, Majid Jobran Lughbi, Amnah Essa Abu Lahsah, Waleed Ali Fehran Alshehri, Nawal Ahmed Alshammari, and Ali Omar Alshargi. "Proton-pump inhibitors use and risk of acute kidney injury." International Journal of Medicine in Developing Countries 3 (2019), 117-119. doi:10.24911/IJMDC.51-1544389362


MLA (The Modern Language Association) Style

Alghamdi, Majed Hassan, Yousef Ali Abdali, Jamilah Saleh Alyami, Hala Ahmed Aljohani, Majid Jobran Lughbi, Amnah Essa Abu Lahsah, Waleed Ali Fehran Alshehri, Nawal Ahmed Alshammari, and Ali Omar Alshargi. "Proton-pump inhibitors use and risk of acute kidney injury." International Journal of Medicine in Developing Countries 3.1 (2019), 117-119. Print. doi:10.24911/IJMDC.51-1544389362


APA (American Psychological Association) Style

Alghamdi, M. H., Abdali, . Y. A., Alyami, . J. S., Aljohani, . H. A., Lughbi, . M. J., Lahsah, . A. E. A., Alshehri, . W. A. F., Alshammari, . N. A. & Alshargi, . A. O. (2019) Proton-pump inhibitors use and risk of acute kidney injury. International Journal of Medicine in Developing Countries, 3 (1), 117-119. doi:10.24911/IJMDC.51-1544389362


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