IJMDC. 2020; 4(10): 1709-1711

Non-operative management of acute appendicitis: a review

Authors: Bashaier Musslum M. Albalawi, Kholood Khalid A. Alolayan, Maryam Rafiah Ansari, Omar Ali M. Alamoudi, Ahdab Abd Ulsattar M. Alsabhi, Abdulrahman Ayeid Abdullah Alshahrani, Ishtiyaq Abdullah A. Abu Zayid, Hamdah Hnef S. Alanazi, Shaden Akram A. Alanazi, Nawaf Farag N. Alomrani, Hussam Ali I. Alzahrani, Fatimah Dirayn M Almarhabi, Abrar Marwan A. Alamrani, Layan Hussain J. Alharbi, Abdulrhman Fadi E. Aljuhani, Ibrahim Mahmoud H. Ajwah.

ABSTRACT

Nonoperative management of acute appendicitis as an alternative to appendectomy is evaluated in randomized control trials for treatment efficacy, perforation, and recurrence of appendicitis. PubMed, Google Scholar, and EBSCO databases were systematically searched for relevant articles. The terms such as acute uncomplicated appendicitis, antibiotic therapy, and nonoperative treatment were used. The initial literature search resulted in 122 records, but only four randomized control trials were found comparing surgery to conservative antibiotic treatment in adult patients with acute appendicitis. The four randomized controlled trails included a total of 1394 patients, of which 684 were treated with surgery and 710 were treated with conservative antibiotic treatment. It was concluded that nonoperative management of acute appendicitis is a safe and effective way to avoid post-operative complication but with a 30% chance of recurrence.

Keywords:
Antibiotic therapy, acute uncomplicated appendicitis, conservative treatment, non-operative treatment, systematic review.


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Non-operative management of acute appendicitis: a review


Authors
Bashaier Musslum M Albalawi
Medical Intern, University of Tabuk, Tabuk, Saudi Arabia
PubMed articlesGoogle scholar articles

Kholood Khalid A Alolayan
Medical Intern, Ibn Sina National College, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Maryam Rafiah Ansari
Medical Intern, Ibn Sina National College, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Omar Ali M Alamoudi
Medical Intern, Ibn Sina National College, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Ahdab Abd Ulsattar M Alsabhi
Medical Intern, Ibn Sina National College, Jeddah, Saudi Arabia
PubMed articlesGoogle scholar articles

Abdulrahman Ayeid Abdullah Alshahrani
Medical Intern, King Khaled University, Abha, Saudi Arabia
PubMed articlesGoogle scholar articles

Ishtiyaq Abdullah A Abu Zayid
Medical Student, University of Tabuk, Tabuk, Saudi Arabia
PubMed articlesGoogle scholar articles

Hamdah Hnef S Alanazi
Medical Student, University of Tabuk, Tabuk, Saudi Arabia
PubMed articlesGoogle scholar articles

Shaden Akram A Alanazi
Medical Student, University of Tabuk, Tabuk, Saudi Arabia
PubMed articlesGoogle scholar articles

Nawaf Farag N Alomrani
Medical Student, University of Tabuk, Tabuk, Saudi Arabia
PubMed articlesGoogle scholar articles

Hussam Ali I Alzahrani
Medical Student, University of Tabuk, Tabuk, Saudi Arabia
PubMed articlesGoogle scholar articles

Fatimah Dirayn M Almarhabi
Medical Intern, University of Tabuk, Tabuk, Saudi Arabia
PubMed articlesGoogle scholar articles

Abrar Marwan A Alamrani
Medical Student, University of Tabuk, Tabuk, Saudi Arabia
PubMed articlesGoogle scholar articles

Layan Hussain J Alharbi
Medical Student, University of Tabuk, Tabuk, Saudi Arabia
PubMed articlesGoogle scholar articles

Abdulrhman Fadi E Aljuhani
Medical Intern, Jordan University of Science and Technology, Jordan
PubMed articlesGoogle scholar articles

Ibrahim Mahmoud H Ajwah
Internal Medicine Resident, King Salman Armed Forces Hospital North West Region, Tabuk, Saudi Arabia
PubMed articlesGoogle scholar articles


Correspondence to:
. Ibrahim Mahmoud H. Ajwah, Internal Medicine Resident, King Salman Armed Forces Hospital North West Region, Tabuk, Saudi Arabia.; aj.wa@hotmail.com

Publication history
Received 16 Sep 2020
Accepted 29 Sep 2020
Published online 05 Oct 2020
Published in print 11 Oct 2020

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Pubmed Style

Albalawi BMM, Alolayan KKA, Ansari MR, Alamoudi OAM, Alsabhi AAUM, Alshahrani AAA, Zayid IAAA, Alanazi HHS, Alanazi SAA, Alomrani NFN, Alzahrani HAI, Almarhabi FDM, Alamrani AMA, Alharbi LHJ, Aljuhani AFE, Ajwah IMH. Non-operative management of acute appendicitis: a review. IJMDC. 2020; 4(10): 1709-1711. doi:10.24911/IJMDC.51-1600300039


Web Style

Albalawi BMM, Alolayan KKA, Ansari MR, Alamoudi OAM, Alsabhi AAUM, Alshahrani AAA, Zayid IAAA, Alanazi HHS, Alanazi SAA, Alomrani NFN, Alzahrani HAI, Almarhabi FDM, Alamrani AMA, Alharbi LHJ, Aljuhani AFE, Ajwah IMH. Non-operative management of acute appendicitis: a review. http://www.ijmdc.com/?mno=135640 [Access: November 26, 2020]. doi:10.24911/IJMDC.51-1600300039


AMA (American Medical Association) Style

Albalawi BMM, Alolayan KKA, Ansari MR, Alamoudi OAM, Alsabhi AAUM, Alshahrani AAA, Zayid IAAA, Alanazi HHS, Alanazi SAA, Alomrani NFN, Alzahrani HAI, Almarhabi FDM, Alamrani AMA, Alharbi LHJ, Aljuhani AFE, Ajwah IMH. Non-operative management of acute appendicitis: a review. IJMDC. 2020; 4(10): 1709-1711. doi:10.24911/IJMDC.51-1600300039


Vancouver/ICMJE Style

Albalawi BMM, Alolayan KKA, Ansari MR, Alamoudi OAM, Alsabhi AAUM, Alshahrani AAA, Zayid IAAA, Alanazi HHS, Alanazi SAA, Alomrani NFN, Alzahrani HAI, Almarhabi FDM, Alamrani AMA, Alharbi LHJ, Aljuhani AFE, Ajwah IMH. Non-operative management of acute appendicitis: a review. IJMDC. (2020), [cited November 26, 2020]; 4(10): 1709-1711. doi:10.24911/IJMDC.51-1600300039


Harvard Style

Albalawi, B. M. M., Alolayan, . K. K. A., Ansari, . M. R., Alamoudi, . O. A. M., Alsabhi, . A. A. U. M., Alshahrani, . A. A. A., Zayid, . I. A. A. A., Alanazi, . H. H. S., Alanazi, . S. A. A., Alomrani, . N. F. N., Alzahrani, . H. A. I., Almarhabi, . F. D. M., Alamrani, . A. M. A., Alharbi, . L. H. J., Aljuhani, . A. F. E. & Ajwah, . I. M. H. (2020) Non-operative management of acute appendicitis: a review. IJMDC, 4 (10), 1709-1711. doi:10.24911/IJMDC.51-1600300039


Turabian Style

Albalawi, Bashaier Musslum M., Kholood Khalid A. Alolayan, Maryam Rafiah Ansari, Omar Ali M. Alamoudi, Ahdab Abd Ulsattar M. Alsabhi, Abdulrahman Ayeid Abdullah Alshahrani, Ishtiyaq Abdullah A. Abu Zayid, Hamdah Hnef S. Alanazi, Shaden Akram A. Alanazi, Nawaf Farag N. Alomrani, Hussam Ali I. Alzahrani, Fatimah Dirayn M Almarhabi, Abrar Marwan A. Alamrani, Layan Hussain J. Alharbi, Abdulrhman Fadi E. Aljuhani, and Ibrahim Mahmoud H. Ajwah. 2020. Non-operative management of acute appendicitis: a review. International Journal of Medicine in Developing Countries, 4 (10), 1709-1711. doi:10.24911/IJMDC.51-1600300039


Chicago Style

Albalawi, Bashaier Musslum M., Kholood Khalid A. Alolayan, Maryam Rafiah Ansari, Omar Ali M. Alamoudi, Ahdab Abd Ulsattar M. Alsabhi, Abdulrahman Ayeid Abdullah Alshahrani, Ishtiyaq Abdullah A. Abu Zayid, Hamdah Hnef S. Alanazi, Shaden Akram A. Alanazi, Nawaf Farag N. Alomrani, Hussam Ali I. Alzahrani, Fatimah Dirayn M Almarhabi, Abrar Marwan A. Alamrani, Layan Hussain J. Alharbi, Abdulrhman Fadi E. Aljuhani, and Ibrahim Mahmoud H. Ajwah. "Non-operative management of acute appendicitis: a review." International Journal of Medicine in Developing Countries 4 (2020), 1709-1711. doi:10.24911/IJMDC.51-1600300039


MLA (The Modern Language Association) Style

Albalawi, Bashaier Musslum M., Kholood Khalid A. Alolayan, Maryam Rafiah Ansari, Omar Ali M. Alamoudi, Ahdab Abd Ulsattar M. Alsabhi, Abdulrahman Ayeid Abdullah Alshahrani, Ishtiyaq Abdullah A. Abu Zayid, Hamdah Hnef S. Alanazi, Shaden Akram A. Alanazi, Nawaf Farag N. Alomrani, Hussam Ali I. Alzahrani, Fatimah Dirayn M Almarhabi, Abrar Marwan A. Alamrani, Layan Hussain J. Alharbi, Abdulrhman Fadi E. Aljuhani, and Ibrahim Mahmoud H. Ajwah. "Non-operative management of acute appendicitis: a review." International Journal of Medicine in Developing Countries 4.10 (2020), 1709-1711. Print. doi:10.24911/IJMDC.51-1600300039


APA (American Psychological Association) Style

Albalawi, B. M. M., Alolayan, . K. K. A., Ansari, . M. R., Alamoudi, . O. A. M., Alsabhi, . A. A. U. M., Alshahrani, . A. A. A., Zayid, . I. A. A. A., Alanazi, . H. H. S., Alanazi, . S. A. A., Alomrani, . N. F. N., Alzahrani, . H. A. I., Almarhabi, . F. D. M., Alamrani, . A. M. A., Alharbi, . L. H. J., Aljuhani, . A. F. E. & Ajwah, . I. M. H. (2020) Non-operative management of acute appendicitis: a review. International Journal of Medicine in Developing Countries, 4 (10), 1709-1711. doi:10.24911/IJMDC.51-1600300039


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